Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 15190..16208 Replicon plasmid pSBAL11703
Accession NC_017578
Organism Shewanella baltica OS117

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag SBAL117_RS24330 Protein ID WP_011840000.1
Coordinates 15639..16208 (+) Length 190 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag SBAL117_RS24325 Protein ID WP_011839999.1
Coordinates 15190..15639 (+) Length 150 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SBAL117_RS24275 10405..10881 + 477 WP_011839993.1 DUF417 family protein -
SBAL117_RS24280 10979..11560 - 582 WP_011839994.1 DUF2913 family protein -
SBAL117_RS24285 11557..11835 - 279 WP_011839995.1 hypothetical protein -
SBAL117_RS25265 12394..12693 + 300 WP_014620443.1 hypothetical protein -
SBAL117_RS24305 12653..13582 + 930 WP_014620444.1 integrase -
SBAL117_RS24310 14134..14409 - 276 WP_148258346.1 hypothetical protein -
SBAL117_RS24315 14424..14678 - 255 WP_011839997.1 Txe/YoeB family addiction module toxin -
SBAL117_RS24320 14675..14926 - 252 WP_011839998.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
SBAL117_RS24325 15190..15639 + 450 WP_011839999.1 helix-turn-helix domain-containing protein Antitoxin
SBAL117_RS24330 15639..16208 + 570 WP_011840000.1 PIN domain-containing protein Toxin
SBAL117_RS24335 16271..17476 - 1206 WP_014620445.1 IS256-like element ISSod5 family transposase -
SBAL117_RS24340 17697..20696 - 3000 WP_014620446.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..71173 71173


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-113)

Antitoxin

Helix-turn-helix domain, group 17

(79-126)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 21664.22 Da        Isoelectric Point: 5.2836

>T27068 WP_011840000.1 NC_017578:15639-16208 [Shewanella baltica OS117]
MASYTVVFDACVMYPAPLRSYLMYLANAGLFRARWTEQIHDEWMRNVLLNNPRITEAMLERTKQLINENVPDCLIEGYEP
LIKGLTLPDMNDRHVVAAALKGHAEAIITFNLKDFPASELNILELSAIHPDEFLCDMFELDLSSCIKAAQQQRSSLKNPP
MTTSEYLNCLQKQRLPVFVSKLRPFELML

Download         Length: 570 bp

>T27068 NC_017578:15639-16208 [Shewanella baltica OS117]
ATGGCTTCGTATACTGTTGTTTTTGATGCGTGTGTCATGTATCCCGCACCACTTCGTAGTTATTTGATGTATTTAGCCAA
TGCGGGCTTATTTAGGGCTCGTTGGACTGAGCAGATCCATGATGAATGGATGCGTAATGTATTGTTGAATAATCCTCGCA
TCACAGAAGCAATGTTAGAACGTACGAAACAACTGATTAATGAAAATGTACCTGATTGCCTTATCGAAGGATATGAGCCG
TTAATTAAAGGATTAACACTGCCTGATATGAATGATAGGCATGTGGTTGCTGCGGCTTTAAAAGGGCATGCAGAGGCCAT
CATAACGTTTAATCTTAAAGATTTTCCTGCATCAGAGCTCAATATACTTGAACTATCAGCTATCCATCCAGATGAGTTTT
TGTGCGACATGTTTGAGTTAGATCTAAGCTCTTGTATCAAAGCTGCTCAACAGCAAAGAAGTAGCTTAAAGAATCCCCCG
ATGACAACATCAGAGTATTTAAATTGCTTACAAAAGCAAAGGTTACCGGTTTTTGTTTCGAAGCTGAGGCCATTTGAATT
AATGCTATAG

Antitoxin


Download         Length: 150 a.a.        Molecular weight: 16606.03 Da        Isoelectric Point: 5.2075

>AT27068 WP_011839999.1 NC_017578:15190-15639 [Shewanella baltica OS117]
MNMTTLPNAEEIAMARLGSQELSAVIESNGEAQQISVIDKQGQSHDVTLPSSVLKMMIEVLTQLGQGNSVNITPIHAEMT
TQQGADFLNMSRPTFIKLLDSREIPFTRVGNRRKVPFSAVIKYKQQLEIQRLSTLDELSRLDQELGMGY

Download         Length: 450 bp

>AT27068 NC_017578:15190-15639 [Shewanella baltica OS117]
ATGAACATGACTACTTTGCCGAACGCCGAAGAAATCGCAATGGCTCGGTTGGGCAGCCAGGAGTTATCTGCTGTTATTGA
AAGTAATGGTGAGGCTCAACAAATAAGTGTAATTGATAAACAAGGTCAATCGCATGATGTCACTTTACCTTCTAGCGTAT
TGAAAATGATGATTGAAGTGTTGACGCAATTGGGGCAGGGTAATTCTGTTAATATCACCCCCATCCATGCCGAAATGACC
ACGCAACAAGGCGCTGACTTTTTGAATATGTCACGGCCAACATTTATCAAGTTATTAGATTCACGTGAAATACCATTTAC
TCGAGTCGGTAATCGAAGAAAAGTGCCATTTTCTGCGGTGATAAAATATAAGCAGCAACTGGAAATCCAGCGTTTGTCAA
CACTTGATGAGCTTTCCAGATTAGATCAGGAATTGGGTATGGGTTACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References