Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | shpAB/BrnT-BrnA |
Location | 4143013..4143589 | Replicon | chromosome |
Accession | NZ_CP117340 | ||
Organism | Salmonella enterica subsp. enterica serovar Dublin strain RM111 |
Toxin (Protein)
Gene name | shpA | Uniprot ID | M7RG88 |
Locus tag | PQQ02_RS20415 | Protein ID | WP_001131963.1 |
Coordinates | 4143302..4143589 (-) | Length | 96 a.a. |
Antitoxin (Protein)
Gene name | shpB | Uniprot ID | A0A5U1K3M6 |
Locus tag | PQQ02_RS20410 | Protein ID | WP_000063141.1 |
Coordinates | 4143013..4143315 (-) | Length | 101 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PQQ02_RS20395 (4139523) | 4139523..4141673 | + | 2151 | WP_000379928.1 | pyruvate/proton symporter BtsT | - |
PQQ02_RS20400 (4141768) | 4141768..4141971 | + | 204 | WP_000460616.1 | YbdD/YjiX family protein | - |
PQQ02_RS20405 (4141982) | 4141982..4142938 | + | 957 | WP_000187843.1 | GTPase | - |
PQQ02_RS20410 (4143013) | 4143013..4143315 | - | 303 | WP_000063141.1 | BrnA antitoxin family protein | Antitoxin |
PQQ02_RS20415 (4143302) | 4143302..4143589 | - | 288 | WP_001131963.1 | BrnT family toxin | Toxin |
PQQ02_RS20420 (4144013) | 4144013..4145854 | + | 1842 | WP_000974635.1 | nuclease-related domain-containing DEAD/DEAH box helicase | - |
PQQ02_RS20425 (4146467) | 4146467..4147042 | + | 576 | WP_000593782.1 | restriction endonuclease subunit S | - |
PQQ02_RS20430 (4147047) | 4147047..4148111 | + | 1065 | WP_223151228.1 | N-6 DNA methylase | - |
PQQ02_RS20435 (4148333) | 4148333..4148467 | - | 135 | WP_001055725.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 96 a.a. Molecular weight: 11294.80 Da Isoelectric Point: 9.5894
>T270639 WP_001131963.1 NZ_CP117340:c4143589-4143302 [Salmonella enterica subsp. enterica serovar Dublin]
MPMEFEWDANKAKSNLRKHGVRFEDAVLVFDDPRHLSRQERYENGEYRWQTLGLVHGIVVILVAHSVRFESGFEVIRIIS
ARKADRKERNRYEHG
MPMEFEWDANKAKSNLRKHGVRFEDAVLVFDDPRHLSRQERYENGEYRWQTLGLVHGIVVILVAHSVRFESGFEVIRIIS
ARKADRKERNRYEHG
Download Length: 288 bp
Antitoxin
Download Length: 101 a.a. Molecular weight: 11431.99 Da Isoelectric Point: 9.8948
>AT270639 WP_000063141.1 NZ_CP117340:c4143315-4143013 [Salmonella enterica subsp. enterica serovar Dublin]
MSMVKHKRGNASALSAQHEAELKALAKKSDDEIDYSDIPASEDGQWSEAVRDKFFRPLKTQASVRIDADVMEWLKRPGKG
YQTRLNAILREAMLREQNKK
MSMVKHKRGNASALSAQHEAELKALAKKSDDEIDYSDIPASEDGQWSEAVRDKFFRPLKTQASVRIDADVMEWLKRPGKG
YQTRLNAILREAMLREQNKK
Download Length: 303 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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