Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 4043302..4043818 Replicon chromosome
Accession NZ_CP117332
Organism Salmonella enterica subsp. enterica serovar Muenster strain RM055

Toxin (Protein)


Gene name relE Uniprot ID C0Q7A9
Locus tag PQP79_RS19635 Protein ID WP_000220578.1
Coordinates 4043302..4043586 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID V7ISI8
Locus tag PQP79_RS19640 Protein ID WP_000212724.1
Coordinates 4043576..4043818 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQP79_RS19620 (4038417) 4038417..4040069 + 1653 WP_023137279.1 alpha,alpha-phosphotrehalase -
PQP79_RS19625 (4040479) 4040479..4042617 + 2139 WP_000187821.1 anaerobic ribonucleoside-triphosphate reductase -
PQP79_RS19630 (4042834) 4042834..4043298 + 465 WP_001009178.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
PQP79_RS19635 (4043302) 4043302..4043586 - 285 WP_000220578.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PQP79_RS19640 (4043576) 4043576..4043818 - 243 WP_000212724.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
PQP79_RS19645 (4043896) 4043896..4045809 - 1914 WP_274880116.1 BglG family transcription antiterminator -
PQP79_RS19650 (4045826) 4045826..4046566 - 741 WP_000779262.1 KDGP aldolase family protein -
PQP79_RS19655 (4046563) 4046563..4047681 - 1119 WP_023137277.1 DgaE family pyridoxal phosphate-dependent ammonia lyase -
PQP79_RS19660 (4047665) 4047665..4048798 - 1134 WP_274881180.1 amidohydrolase/deacetylase family metallohydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-80)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10854.67 Da        Isoelectric Point: 10.0482

>T270573 WP_000220578.1 NZ_CP117332:c4043586-4043302 [Salmonella enterica subsp. enterica serovar Muenster]
MTYELEFDPRALKEWHKLGDTVKAQLKKKLADVLLNPRIDSARLNGLPDCYKIKLKSSGYRLVYQVRDDVVIVFVVAVGK
REHSAVYHDANKRL

Download         Length: 285 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8961.34 Da        Isoelectric Point: 5.0651

>AT270573 WP_000212724.1 NZ_CP117332:c4043818-4043576 [Salmonella enterica subsp. enterica serovar Muenster]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGRMPVKTVTLSDSEDALIQTVRERLSSPQKGIKVSLDDL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Z1E876

Antitoxin

Source ID Structure
AlphaFold DB A0A5H5JRI5

References