270564

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 831392..832052 Replicon chromosome
Accession NZ_CP117332
Organism Salmonella enterica subsp. enterica serovar Muenster strain RM055

Toxin (Protein)


Gene name cptA Uniprot ID A0A5I1G658
Locus tag PQP79_RS04000 Protein ID WP_001727955.1
Coordinates 831639..832052 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag PQP79_RS03995 Protein ID WP_000351186.1
Coordinates 831392..831658 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQP79_RS03975 (827321) 827321..828754 - 1434 WP_023136672.1 6-phospho-beta-glucosidase BglA -
PQP79_RS03980 (828912) 828912..829223 + 312 WP_001182972.1 N(4)-acetylcytidine aminohydrolase -
PQP79_RS03985 (829387) 829387..830046 + 660 WP_000250289.1 hemolysin III family protein -
PQP79_RS03990 (830162) 830162..831142 - 981 WP_000874169.1 tRNA-modifying protein YgfZ -
PQP79_RS03995 (831392) 831392..831658 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
PQP79_RS04000 (831639) 831639..832052 + 414 WP_001727955.1 protein YgfX Toxin
PQP79_RS04005 (832105) 832105..832626 - 522 WP_001055885.1 flavodoxin FldB -
PQP79_RS04010 (832739) 832739..833635 + 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
PQP79_RS04015 (833659) 833659..834372 + 714 WP_000745614.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
PQP79_RS04020 (834378) 834378..836111 + 1734 WP_000813387.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16201.18 Da        Isoelectric Point: 10.7537

>T270564 WP_001727955.1 NZ_CP117332:831639-832052 [Salmonella enterica subsp. enterica serovar Muenster]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMMLLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLRPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT270564 WP_000351186.1 NZ_CP117332:831392-831658 [Salmonella enterica subsp. enterica serovar Muenster]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A5I1G658

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References