Detailed information of TA system TA027056

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/LOTUS_5_Limkain_b1-Phd
• Location: 2613253..2613914
• Replicon: chromosome
• Accession: NC_017574
• Organism: Ralstonia solanacearum Po82

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: F6G2N5
• Locus tag: RSPO_RS11960
• Protein ID: WP_014617593.1
• Coordinates: 2613501..2613914 (+)
• Length: 138 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: F6G2N4
• Locus tag: RSPO_RS11955
• Protein ID: WP_014617592.1
• Coordinates: 2613253..2613504 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RSPO_RS11945	2608677..2609072	-	396	WP_014617590.1	hypothetical protein	-
RSPO_RS11950	2609078..2613178	-	4101	WP_014617591.1	phage tail tape measure protein	-
RSPO_RS11955	2613253..2613504	+	252	WP_014617592.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
RSPO_RS11960	2613501..2613914	+	414	WP_014617593.1	type II toxin-antitoxin system VapC family toxin	Toxin
RSPO_RS11965	2613919..2614152	-	234	WP_124994719.1	hypothetical protein	-
RSPO_RS11970	2614352..2615818	+	1467	WP_014617595.1	YOPP/AvrRxv family protein	-
RSPO_RS11975	2616013..2616303	+	291	WP_014617596.1	H-NS histone family protein	-
RSPO_RS11980	2616346..2616990	-	645	WP_014617597.1	hypothetical protein	-
RSPO_RS11985	2616965..2617186	-	222	WP_014617598.1	hypothetical protein	-
RSPO_RS11990	2617183..2617575	-	393	WP_014617599.1	hypothetical protein	-
RSPO_RS11995	2617584..2618357	-	774	WP_014617600.1	hypothetical protein	-
RSPO_RS12000	2618465..2618911	-	447	WP_014617601.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2587639..2667742	80103

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (3-122)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-63)

Sequences

Toxin

Protein

• Length: 138 a.a.
• Molecular weight: 15723.04 Da
• Isoelectric Point: 6.0853

>T27056 WP_014617593.1 NC_017574:2613501-2613914 [Ralstonia solanacearum Po82]
MSYLVDTNVLSELRRKQPDAHVLAWMQDRPRQSLYLSVLTLGEIRKGIERLDDAARRQHLIDWLETELPNYFLGRLLDID
AHTADRWGRLMSSANRPLPAIDGLLAATALQHDLILVTRNTKDFVGLDVPLINPWET

Nucleotide

• Length: 414 bp

>T27056 NC_017574:2613501-2613914 [Ralstonia solanacearum Po82]
TTGAGTTACCTGGTCGACACCAATGTCCTGTCCGAGCTACGCCGCAAGCAGCCCGATGCGCACGTGCTCGCGTGGATGCA
AGACCGGCCGCGCCAGTCGCTCTACCTGAGCGTGCTGACCCTGGGCGAAATCCGCAAAGGCATCGAGCGGCTGGACGACG
CAGCACGCCGCCAGCACCTGATCGACTGGCTCGAAACGGAACTGCCGAACTACTTCCTCGGCCGCTTGCTCGACATCGAT
GCCCATACCGCCGACCGCTGGGGCCGGCTGATGTCGAGCGCCAACCGGCCGCTGCCGGCCATCGACGGCCTGCTCGCCGC
GACCGCCCTGCAGCACGACCTCATACTGGTCACGCGTAACACGAAGGATTTCGTCGGACTCGACGTCCCGCTCATCAACC
CGTGGGAAACGTGA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9256.49 Da
• Isoelectric Point: 5.0774

>AT27056 WP_014617592.1 NC_017574:2613253-2613504 [Ralstonia solanacearum Po82]
MQSWQLQAAKARFSDVVKRAADDGPQEITVHGRPVAVVISRALFDRLSGGGESLVDFMRQSPLAGLDDVVFERERSLPRE
IEF

Nucleotide

• Length: 252 bp

>AT27056 NC_017574:2613253-2613504 [Ralstonia solanacearum Po82]
ATGCAAAGCTGGCAGTTGCAAGCCGCCAAGGCGCGGTTTTCCGACGTCGTGAAGCGTGCAGCGGATGATGGTCCGCAGGA
AATCACGGTGCATGGCCGCCCGGTCGCAGTTGTGATCTCGCGCGCACTGTTCGATCGCCTGAGTGGCGGCGGTGAGTCGC
TGGTCGACTTCATGCGCCAGTCTCCGTTGGCTGGCCTGGACGACGTCGTCTTCGAGCGCGAACGCAGCCTGCCGCGCGAG
ATCGAGTTTTGA

Structures

Toxin

• AlphaFold DB: F6G2N5

Antitoxin

• AlphaFold DB: F6G2N4