Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 831381..832041 Replicon chromosome
Accession NZ_CP117329
Organism Salmonella enterica subsp. enterica serovar Muenster strain RM074

Toxin (Protein)


Gene name cptA Uniprot ID A0A5I1G658
Locus tag PQP80_RS04000 Protein ID WP_001727955.1
Coordinates 831628..832041 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag PQP80_RS03995 Protein ID WP_000351186.1
Coordinates 831381..831647 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQP80_RS03975 (827310) 827310..828743 - 1434 WP_023136672.1 6-phospho-beta-glucosidase BglA -
PQP80_RS03980 (828901) 828901..829212 + 312 WP_001182972.1 N(4)-acetylcytidine aminohydrolase -
PQP80_RS03985 (829376) 829376..830035 + 660 WP_000250289.1 hemolysin III family protein -
PQP80_RS03990 (830151) 830151..831131 - 981 WP_000874169.1 tRNA-modifying protein YgfZ -
PQP80_RS03995 (831381) 831381..831647 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
PQP80_RS04000 (831628) 831628..832041 + 414 WP_001727955.1 protein YgfX Toxin
PQP80_RS04005 (832094) 832094..832615 - 522 WP_001055885.1 flavodoxin FldB -
PQP80_RS04010 (832728) 832728..833624 + 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
PQP80_RS04015 (833648) 833648..834361 + 714 WP_000745614.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
PQP80_RS04020 (834367) 834367..836100 + 1734 WP_274880277.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16201.18 Da        Isoelectric Point: 10.7537

>T270547 WP_001727955.1 NZ_CP117329:831628-832041 [Salmonella enterica subsp. enterica serovar Muenster]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMMLLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLRPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT270547 WP_000351186.1 NZ_CP117329:831381-831647 [Salmonella enterica subsp. enterica serovar Muenster]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A5I1G658

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References