270540

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2038..2573 Replicon plasmid pRM106_1
Accession NZ_CP117328
Organism Salmonella enterica subsp. enterica serovar Saintpaul strain RM106

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PQP95_RS22760 Protein ID WP_000221869.1
Coordinates 2286..2573 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PQP95_RS22755 Protein ID WP_001132897.1
Coordinates 2038..2289 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQP95_RS22750 (46) 46..1077 + 1032 WP_000907870.1 plasmid replication initiator RepA -
PQP95_RS22755 (2038) 2038..2289 + 252 WP_001132897.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PQP95_RS22760 (2286) 2286..2573 + 288 WP_000221869.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PQP95_RS22765 (2879) 2879..4046 - 1168 Protein_3 IS91 family transposase -
PQP95_RS22770 (4050) 4050..4241 - 192 WP_228452813.1 transposase -
PQP95_RS22775 (4391) 4391..4573 + 183 Protein_5 helix-turn-helix domain-containing protein -
PQP95_RS22780 (5605) 5605..6333 + 729 WP_000497521.1 hypothetical protein -
PQP95_RS22785 (6398) 6398..6898 + 501 WP_000840063.1 CS1 type fimbrial major subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid floR / tet(A) / aph(6)-Id / aph(3'')-Ib / sul2 / blaTEM-1A - 1..114639 114639


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11179.35 Da        Isoelectric Point: 10.5828

>T270540 WP_000221869.1 NZ_CP117328:2286-2573 [Salmonella enterica subsp. enterica serovar Saintpaul]
MTYMVKFRDDALKEWLKLDKTIQRQFAKKLKKCSDNPHIPSAKLRGLKDCYKIKLRASGFRLVYQVIDDMLIIAVVAVGK
RERCNVYNLASERMR

Download         Length: 288 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9239.47 Da        Isoelectric Point: 4.0927

>AT270540 WP_001132897.1 NZ_CP117328:2038-2289 [Salmonella enterica subsp. enterica serovar Saintpaul]
MPNIILSDTSASVSELKKNPMATVSAGDGYPVAILNRNQPAFYCIPAELYERMLDALDDQELVKLVTERSNQPLHEVDLD
SYL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References