Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2022351..2022496 Replicon chromosome
Accession NZ_CP117326
Organism Salmonella enterica subsp. enterica serovar Newport strain RM108

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2022391..2022494 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2022351..2022496 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQQ05_RS09725 2018777..2019475 - 699 WP_000944285.1 exodeoxyribonuclease X -
PQQ05_RS09730 2019526..2020155 - 630 WP_274895574.1 carbon-nitrogen hydrolase family protein -
PQQ05_RS09735 2020263..2020493 - 231 WP_000856224.1 DNA polymerase III subunit theta -
PQQ05_RS09740 2020631..2021005 + 375 WP_000168395.1 CopC domain-containing protein YobA -
PQQ05_RS09745 2021006..2021881 + 876 WP_000979686.1 copper homeostasis membrane protein CopD -
PQQ05_RS09750 2021898..2022251 + 354 WP_000722368.1 YebY family protein -
- 2022351..2022496 - 146 - - Antitoxin
- 2022391..2022494 + 104 - - Toxin
PQQ05_RS09755 2022624..2023703 - 1080 WP_000087646.1 phage integrase Arm DNA-binding domain-containing protein -
PQQ05_RS09760 2023733..2024728 - 996 Protein_1905 PD-(D/E)XK nuclease-like domain-containing protein -
PQQ05_RS09765 2024876..2025124 + 249 Protein_1906 glycoside hydrolase family 19 protein -
PQQ05_RS09770 2025121..2025655 + 535 Protein_1907 DUF2514 domain-containing protein -
PQQ05_RS09775 2025912..2026079 - 168 WP_000789530.1 lytic enzyme -
PQQ05_RS09780 2026144..2026332 - 189 WP_001521334.1 hypothetical protein -
PQQ05_RS09785 2026387..2026647 + 261 Protein_1910 DUF1441 family protein -
PQQ05_RS09790 2026862..2027206 + 345 Protein_1911 macro domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 2016689..2062252 45563
- inside Prophage - sopE2 2000480..2062252 61772


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T270510 NZ_CP117326:2022391-2022494 [Salmonella enterica subsp. enterica serovar Newport]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT270510 NZ_CP117326:c2022496-2022351 [Salmonella enterica subsp. enterica serovar Newport]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References