Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | tacAT/DUF1778(antitoxin) |
Location | 4257307..4258088 | Replicon | chromosome |
Accession | NZ_CP117317 | ||
Organism | Salmonella enterica subsp. enterica serovar Derby strain RM002 |
Toxin (Protein)
Gene name | TacT2 | Uniprot ID | A0A3Y7QYP9 |
Locus tag | PQQ14_RS20635 | Protein ID | WP_023231674.1 |
Coordinates | 4257307..4257798 (-) | Length | 164 a.a. |
Antitoxin (Protein)
Gene name | TacA2 | Uniprot ID | A0A3Y7QYQ5 |
Locus tag | PQQ14_RS20640 | Protein ID | WP_023231675.1 |
Coordinates | 4257795..4258088 (-) | Length | 98 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PQQ14_RS20610 (4254188) | 4254188..4255018 | - | 831 | WP_023231671.1 | fimbria/pilus periplasmic chaperone | - |
PQQ14_RS20615 (4255220) | 4255220..4255525 | - | 306 | WP_000370555.1 | PapB/FocB family fimbrial expression transcriptional regulator | - |
PQQ14_RS20620 (4256057) | 4256057..4256200 | + | 144 | Protein_4033 | transposase | - |
PQQ14_RS20625 (4256217) | 4256217..4256563 | + | 347 | Protein_4034 | Rpn family recombination-promoting nuclease/putative transposase | - |
PQQ14_RS20630 (4256844) | 4256844..4257092 | - | 249 | Protein_4035 | IS481 family transposase | - |
PQQ14_RS20635 (4257307) | 4257307..4257798 | - | 492 | WP_023231674.1 | GNAT family N-acetyltransferase | Toxin |
PQQ14_RS20640 (4257795) | 4257795..4258088 | - | 294 | WP_023231675.1 | DUF1778 domain-containing protein | Antitoxin |
PQQ14_RS20645 (4258406) | 4258406..4258628 | + | 223 | Protein_4038 | hypothetical protein | - |
PQQ14_RS20650 (4258894) | 4258894..4259769 | + | 876 | WP_023195838.1 | AraC family transcriptional regulator | - |
PQQ14_RS20655 (4259766) | 4259766..4260053 | + | 288 | WP_001269916.1 | transcriptional regulator RtsB | - |
PQQ14_RS20660 (4260046) | 4260046..4260228 | - | 183 | WP_023231676.1 | ATP-binding cassette domain-containing protein | - |
PQQ14_RS20665 (4260248) | 4260248..4260347 | + | 100 | Protein_4042 | hypothetical protein | - |
PQQ14_RS20670 (4260455) | 4260455..4260589 | + | 135 | Protein_4043 | hypothetical protein | - |
PQQ14_RS20675 (4260884) | 4260884..4261789 | - | 906 | WP_023231677.1 | YjiK family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 164 a.a. Molecular weight: 17643.45 Da Isoelectric Point: 7.2655
>T270482 WP_023231674.1 NZ_CP117317:c4257798-4257307 [Salmonella enterica subsp. enterica serovar Derby]
MISPPEPLHAGHILTPFCCGVDSMDNWLKQRAMKNQATGASRTFVCCGSDSNVLAYYSLASSAVTTNTAPGRFRRNMPDP
IPIVVLGRLAVDKSLHGQGVGRALVRDAGLRVIQVAETIGIRGMLVHALSDEAREFYQRVGFEPSPMDPMMLMVTLGDLV
ESV
MISPPEPLHAGHILTPFCCGVDSMDNWLKQRAMKNQATGASRTFVCCGSDSNVLAYYSLASSAVTTNTAPGRFRRNMPDP
IPIVVLGRLAVDKSLHGQGVGRALVRDAGLRVIQVAETIGIRGMLVHALSDEAREFYQRVGFEPSPMDPMMLMVTLGDLV
ESV
Download Length: 492 bp
Antitoxin
Download Length: 98 a.a. Molecular weight: 10930.60 Da Isoelectric Point: 9.8590
>AT270482 WP_023231675.1 NZ_CP117317:c4258088-4257795 [Salmonella enterica subsp. enterica serovar Derby]
MPAANSMAMKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIEQRIIMADPQAYQEFLARLDQAPVPN
AALRKTMQTPAPWEQEK
MPAANSMAMKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIEQRIIMADPQAYQEFLARLDQAPVPN
AALRKTMQTPAPWEQEK
Download Length: 294 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A3Y7QYP9 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A3Y7QYQ5 |