Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2130729..2130872 Replicon chromosome
Accession NZ_CP117292
Organism Salmonella enterica subsp. enterica serovar Typhi strain S4

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2130768..2130870 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2130729..2130872 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PRW96_RS10225 (PRW96_10225) 2127153..2127851 - 699 WP_000944282.1 exodeoxyribonuclease X -
PRW96_RS10230 (PRW96_10230) 2127875..2128531 - 657 WP_000100250.1 carbon-nitrogen hydrolase family protein -
PRW96_RS10235 (PRW96_10235) 2128639..2128869 - 231 WP_000856224.1 DNA polymerase III subunit theta -
PRW96_RS10240 (PRW96_10240) 2129007..2129381 + 375 WP_001681742.1 CopC domain-containing protein YobA -
PRW96_RS10245 (PRW96_10245) 2129382..2130257 + 876 WP_000979693.1 copper homeostasis membrane protein CopD -
PRW96_RS10250 (PRW96_10250) 2130274..2130627 + 354 WP_000722366.1 YebY family protein -
- 2130729..2130872 - 144 - - Antitoxin
- 2130768..2130870 + 103 - - Toxin
PRW96_RS10255 (PRW96_10255) 2130991..2131299 - 309 Protein_1992 tyrosine-type recombinase/integrase -
PRW96_RS10260 (PRW96_10260) 2131298..2131659 - 362 Protein_1993 recombinase RecT -
PRW96_RS10265 (PRW96_10265) 2131660..2131770 + 111 Protein_1994 replication protein -
PRW96_RS10270 (PRW96_10270) 2131783..2132178 + 396 Protein_1995 DUF977 family protein -
PRW96_RS10275 (PRW96_10275) 2132464..2133594 - 1131 WP_000529513.1 GGDEF domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 2125065..2162059 36994


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T270276 NZ_CP117292:2130768-2130870 [Salmonella enterica subsp. enterica serovar Typhi]
GCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 144 bp

>AT270276 NZ_CP117292:c2130872-2130729 [Salmonella enterica subsp. enterica serovar Typhi]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCTCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References