Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2777296..2777439 Replicon chromosome
Accession NZ_CP117291
Organism Salmonella enterica subsp. enterica serovar Typhi strain S5

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2777298..2777400 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2777296..2777439 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PRW97_RS13880 (PRW97_13880) 2774574..2775704 + 1131 WP_000529513.1 GGDEF domain-containing protein -
PRW97_RS13885 (PRW97_13885) 2775990..2776385 - 396 Protein_2721 DUF977 family protein -
PRW97_RS13890 (PRW97_13890) 2776398..2776508 - 111 Protein_2722 replication protein -
PRW97_RS13895 (PRW97_13895) 2776509..2776870 + 362 Protein_2723 recombinase RecT -
PRW97_RS13900 (PRW97_13900) 2776869..2777177 + 309 Protein_2724 tyrosine-type recombinase/integrase -
- 2777296..2777439 + 144 - - Antitoxin
- 2777298..2777400 - 103 - - Toxin
PRW97_RS13905 (PRW97_13905) 2777541..2777894 - 354 WP_000722366.1 YebY family protein -
PRW97_RS13910 (PRW97_13910) 2777911..2778786 - 876 WP_000979693.1 copper homeostasis membrane protein CopD -
PRW97_RS13915 (PRW97_13915) 2778787..2779161 - 375 WP_001681742.1 CopC domain-containing protein YobA -
PRW97_RS13920 (PRW97_13920) 2779299..2779529 + 231 WP_000856224.1 DNA polymerase III subunit theta -
PRW97_RS13925 (PRW97_13925) 2779637..2780293 + 657 WP_000100250.1 carbon-nitrogen hydrolase family protein -
PRW97_RS13930 (PRW97_13930) 2780317..2781015 + 699 WP_000944282.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 2746109..2783103 36994


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T270260 NZ_CP117291:c2777400-2777298 [Salmonella enterica subsp. enterica serovar Typhi]
GCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 144 bp

>AT270260 NZ_CP117291:2777296-2777439 [Salmonella enterica subsp. enterica serovar Typhi]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCTCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References