Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 1157286..1157971 Replicon plasmid unnamed1
Accession NZ_CP117268
Organism Rhizobium rhododendri strain rho-6.2

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PR018_RS23060 Protein ID WP_142832619.1
Coordinates 1157549..1157971 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PR018_RS23055 Protein ID WP_142832620.1
Coordinates 1157286..1157552 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PR018_RS23035 (PR018_23040) 1153467..1154051 - 585 WP_219271068.1 plasmid pRiA4b ORF-3 family protein -
PR018_RS23040 (PR018_23045) 1154051..1155709 - 1659 WP_142832615.1 IS66 family transposase -
PR018_RS23045 (PR018_23050) 1155787..1156134 - 348 WP_046119556.1 IS66 family insertion sequence element accessory protein TnpB -
PR018_RS23050 (PR018_23055) 1156131..1156478 - 348 WP_111217014.1 transposase -
PR018_RS23055 (PR018_23060) 1157286..1157552 + 267 WP_142832620.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PR018_RS23060 (PR018_23065) 1157549..1157971 + 423 WP_142832619.1 type II toxin-antitoxin system VapC family toxin Toxin
PR018_RS23065 (PR018_23070) 1158074..1159198 + 1125 WP_143123525.1 IS5 family transposase -
PR018_RS23070 (PR018_23075) 1159352..1159813 + 462 WP_142832600.1 hypothetical protein -
PR018_RS23075 (PR018_23080) 1160377..1160798 - 422 Protein_1039 MucR family transcriptional regulator -
PR018_RS23080 (PR018_23085) 1161340..1161663 + 324 WP_142832599.1 hypothetical protein -
PR018_RS23085 (PR018_23090) 1161809..1161934 - 126 WP_257625516.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB / htpB 1..1530638 1530638
- inside IScluster/Tn - - 1155787..1159198 3411


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-125)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-72)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15618.02 Da        Isoelectric Point: 5.2203

>T270222 WP_142832619.1 NZ_CP117268:1157549-1157971 [Rhizobium rhododendri]
MRLLLDTNVLSEVTKPRPAECVLNWLHGLDEDRTFISIVSIAEIRRGVALMDIGRKRDALDTWLTHDLPQRFDNRIIPVE
AHLALAWGDLMALAKRSGRGLASMDGLIAATAVARDLTLATRNTKDFEGFGIDLVDPWEV

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9695.99 Da        Isoelectric Point: 7.0157

>AT270222 WP_142832620.1 NZ_CP117268:1157286-1157552 [Rhizobium rhododendri]
MRASTHNDMSWTVAGAKARLSEVMERAQAAPQTITRNGKPSVVVVSAEEWEKKTARRGSLAEFLLASPLRGADMDIERLS
DEPRDLSL

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References