Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 816865..817445 Replicon plasmid unnamed1
Accession NZ_CP117268
Organism Rhizobium rhododendri strain rho-6.2

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PR018_RS21515 Protein ID WP_142831763.1
Coordinates 816865..817248 (-) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PR018_RS21520 Protein ID WP_142831764.1
Coordinates 817245..817445 (-) Length 67 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PR018_RS21500 (PR018_21500) 812218..814221 + 2004 WP_142831760.1 aldo/keto reductase -
PR018_RS21505 (PR018_21505) 814714..815538 - 825 WP_142831761.1 hypothetical protein -
PR018_RS21510 (PR018_21510) 815522..816595 - 1074 WP_142831762.1 AAA family ATPase -
PR018_RS21515 (PR018_21515) 816865..817248 - 384 WP_142831763.1 type II toxin-antitoxin system VapC family toxin Toxin
PR018_RS21520 (PR018_21520) 817245..817445 - 201 WP_142831764.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
PR018_RS21525 (PR018_21525) 817576..818580 - 1005 WP_142831765.1 C-terminal binding protein -
PR018_RS21530 (PR018_21530) 818585..819556 - 972 WP_142831766.1 2-dehydropantoate 2-reductase N-terminal domain-containing protein -
PR018_RS21535 (PR018_21535) 819569..820750 - 1182 WP_142831767.1 acyl-CoA dehydrogenase family protein -
PR018_RS21540 (PR018_21540) 820870..821973 - 1104 WP_142831768.1 LLM class flavin-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB / htpB 1..1530638 1530638


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-42)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 13951.20 Da        Isoelectric Point: 8.1224

>T270221 WP_142831763.1 NZ_CP117268:c817248-816865 [Rhizobium rhododendri]
VILVDTSIWIDHFRHGDVELRKVIADDLLLCHPVVVGELALGSLRDRGAVMAFFSAQREALVASHYEVITMIGRHSIFSM
GIGYTDAHLLASILLDRRSLLWTRDKRLAAAARKAGASLYAPTSAPN

Download         Length: 384 bp

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7125.13 Da        Isoelectric Point: 10.4525

>AT270221 WP_142831764.1 NZ_CP117268:c817445-817245 [Rhizobium rhododendri]
MRSTINLDDNLMEQARSLTGTKETAALVRQALETLVRVESGKRLAALGGTMPDAEAAPRRRSEAAK

Download         Length: 201 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References