Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 467547..468211 Replicon plasmid unnamed1
Accession NZ_CP117268
Organism Rhizobium rhododendri strain rho-6.2

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PR018_RS19925 Protein ID WP_142831606.1
Coordinates 467783..468211 (+) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PR018_RS19920 Protein ID WP_142831607.1
Coordinates 467547..467786 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PR018_RS19890 (PR018_19890) 462918..463400 + 483 WP_142831612.1 chemotaxis protein CheW -
PR018_RS19895 (PR018_19895) 463677..464558 + 882 WP_142831611.1 HD-GYP domain-containing protein -
PR018_RS19900 (PR018_19900) 464697..464906 + 210 WP_142831610.1 hypothetical protein -
PR018_RS19905 (PR018_19905) 465595..465939 - 345 WP_142831609.1 hypothetical protein -
PR018_RS19910 (PR018_19910) 466289..466537 + 249 WP_142831608.1 hypothetical protein -
PR018_RS19915 (PR018_19915) 466577..467291 + 715 Protein_407 IS6 family transposase -
PR018_RS19920 (PR018_19920) 467547..467786 + 240 WP_142831607.1 Arc family DNA-binding protein Antitoxin
PR018_RS19925 (PR018_19925) 467783..468211 + 429 WP_142831606.1 type II toxin-antitoxin system VapC family toxin Toxin
PR018_RS19930 (PR018_19930) 468283..468573 + 291 WP_142831605.1 hypothetical protein -
PR018_RS19935 (PR018_19935) 468842..469537 - 696 WP_142831604.1 alpha/beta hydrolase -
PR018_RS19940 (PR018_19940) 469877..470551 - 675 WP_244615504.1 permease -
PR018_RS19945 (PR018_19945) 470931..471359 - 429 WP_142831602.1 hypothetical protein -
PR018_RS19950 (PR018_19950) 471582..472409 - 828 WP_142831601.1 aldo/keto reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB / htpB 1..1530638 1530638
- flank IS/Tn - - 466577..467173 596


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin

Arc-like DNA binding domain

(9-46)


Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15196.45 Da        Isoelectric Point: 5.8927

>T270220 WP_142831606.1 NZ_CP117268:467783-468211 [Rhizobium rhododendri]
MILLDTNVISEPLKSQPDPRVAAWIDTQAVETLYVAAISLAELRYGIAVHPDGKKKQAAQEKLDRLMLPLFRGRIMPFDE
AAAQAYAELRAAAAKKGKAIGDSDGYIAATAKANGLMIATRDTSPFEAAGLTVINPWEASNG

Download         Length: 429 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8652.88 Da        Isoelectric Point: 7.2054

>AT270220 WP_142831607.1 NZ_CP117268:467547-467786 [Rhizobium rhododendri]
MASITIRNVPDEVHRALRVRAAQHGRSAEAEIRIILEQAAKPEGRVKLGSLLTQIGQEVGGLDLTIERDRTPSPPVSFE

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References