Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 1971704..1972300 Replicon chromosome
Accession NZ_CP117267
Organism Rhizobium rhododendri strain rho-6.2

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PR018_RS09645 Protein ID WP_142823292.1
Coordinates 1972007..1972300 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag PR018_RS09640 Protein ID WP_142823291.1
Coordinates 1971704..1972006 (-) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PR018_RS09620 (PR018_09620) 1968789..1969124 + 336 WP_142823289.1 BrnA antitoxin family protein -
PR018_RS09625 (PR018_09625) 1969369..1969545 + 177 WP_153816481.1 hypothetical protein -
PR018_RS09630 (PR018_09630) 1969721..1970173 - 453 WP_142823290.1 GatB/YqeY domain-containing protein -
PR018_RS09635 (PR018_09635) 1970459..1971664 + 1206 WP_142823609.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
PR018_RS09640 (PR018_09640) 1971704..1972006 - 303 WP_142823291.1 putative addiction module antidote protein Antitoxin
PR018_RS09645 (PR018_09645) 1972007..1972300 - 294 WP_142823292.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PR018_RS09650 (PR018_09650) 1972383..1973789 - 1407 WP_142823293.1 MATE family efflux transporter -
PR018_RS09655 (PR018_09655) 1973936..1975174 - 1239 WP_142829287.1 TCR/Tet family MFS transporter -
PR018_RS09660 (PR018_09660) 1975345..1976256 - 912 WP_142823295.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-94)

Antitoxin

Uncharacterized protein HI1420

(8-97)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11253.10 Da        Isoelectric Point: 10.6024

>T270219 WP_142823292.1 NZ_CP117267:c1972300-1972007 [Rhizobium rhododendri]
MLEVRQTILFRRWFDGLKDKRAVERITQRIVRLQAGLFGDIKFFDGIGELRVDHGPGYRVYFVQRGSVLVILLWGGDKSS
QTRDIRKAKAMADDLEI

Download         Length: 294 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10452.03 Da        Isoelectric Point: 8.5285

>AT270219 WP_142823291.1 NZ_CP117267:c1972006-1971704 [Rhizobium rhododendri]
MPVKTLPFDAADHLQSGQSQLELLSDAFNSGSASYVAVALGVIARAKGMTEVSKTAGITREALYKALSADGDPKLSTLLG
VLNALDIQLKLAPRNKKAPD

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References