Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 1441439..1442043 Replicon chromosome
Accession NZ_CP117267
Organism Rhizobium rhododendri strain rho-6.2

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PR018_RS07165 Protein ID WP_142822785.1
Coordinates 1441439..1441744 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PR018_RS07170 Protein ID WP_142822787.1
Coordinates 1441741..1442043 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PR018_RS07145 (PR018_07145) 1436874..1437236 + 363 WP_142822779.1 glycine cleavage system protein GcvH -
PR018_RS07150 (PR018_07150) 1437236..1440100 + 2865 WP_142829148.1 aminomethyl-transferring glycine dehydrogenase -
PR018_RS07155 (PR018_07155) 1440137..1440760 - 624 WP_142822782.1 LysE family transporter -
PR018_RS07160 (PR018_07160) 1440856..1441248 - 393 WP_142822784.1 Fe-S cluster assembly scaffold SufA -
PR018_RS07165 (PR018_07165) 1441439..1441744 + 306 WP_142822785.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PR018_RS07170 (PR018_07170) 1441741..1442043 + 303 WP_142822787.1 putative addiction module antidote protein Antitoxin
PR018_RS07175 (PR018_07175) 1442044..1442424 - 381 WP_142822788.1 SUF system Fe-S cluster assembly protein -
PR018_RS07180 (PR018_07180) 1442539..1443780 - 1242 WP_142822791.1 cysteine desulfurase -
PR018_RS07185 (PR018_07185) 1443793..1445067 - 1275 WP_142822793.1 Fe-S cluster assembly protein SufD -
PR018_RS07190 (PR018_07190) 1445090..1445845 - 756 WP_142822795.1 Fe-S cluster assembly ATPase SufC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-96)

Antitoxin

Uncharacterized protein HI1420

(4-91)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11896.78 Da        Isoelectric Point: 10.7321

>T270218 WP_142822785.1 NZ_CP117267:1441439-1441744 [Rhizobium rhododendri]
VFVIQRTEIFQQWIMRLKDRSAAARIASRILRAEDGNLRDVKPVGDGVEEMRIDYGPGYRIYFLRRRSVFVVLLVGGDKS
TQRRDIIEAKRLCAEWKERNQ

Download         Length: 306 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10482.99 Da        Isoelectric Point: 5.0651

>AT270218 WP_142822787.1 NZ_CP117267:1441741-1442043 [Rhizobium rhododendri]
MTSDTRLFDASEVLDSESAIDEFLAAAFETEDPAFIAKSLGVIAKTRNMSAIARDVGMSRAALYKSLSGKGNPEFATIIK
VMKALGLGLAPVSRSNQGAA

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References