Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 928930..929517 Replicon chromosome
Accession NZ_CP117267
Organism Rhizobium rhododendri strain rho-6.2

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PR018_RS04635 Protein ID WP_142829519.1
Coordinates 929227..929517 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PR018_RS04630 Protein ID WP_142829521.1
Coordinates 928930..929226 (-) Length 99 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PR018_RS04610 (PR018_04610) 924894..925847 + 954 WP_224128276.1 murein L,D-transpeptidase catalytic domain family protein -
PR018_RS04615 (PR018_04615) 925893..926684 - 792 WP_142829526.1 sulfite exporter TauE/SafE family protein -
PR018_RS04620 (PR018_04620) 926707..927639 - 933 WP_142829524.1 N-acetyl-gamma-glutamyl-phosphate reductase -
PR018_RS04625 (PR018_04625) 927722..928675 - 954 WP_142829522.1 agmatinase -
PR018_RS04630 (PR018_04630) 928930..929226 - 297 WP_142829521.1 putative addiction module antidote protein Antitoxin
PR018_RS04635 (PR018_04635) 929227..929517 - 291 WP_142829519.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PR018_RS04640 (PR018_04640) 929642..930112 - 471 WP_111220548.1 30S ribosomal protein S9 -
PR018_RS04645 (PR018_04645) 930115..930579 - 465 WP_111220549.1 50S ribosomal protein L13 -
PR018_RS04650 (PR018_04650) 931173..931499 - 327 WP_142829518.1 hypothetical protein -
PR018_RS04655 (PR018_04655) 931609..932040 + 432 WP_142829516.1 CoA-binding protein -
PR018_RS04660 (PR018_04660) 932159..933442 + 1284 WP_142829514.1 O-acetylhomoserine aminocarboxypropyltransferase -
PR018_RS04665 (PR018_04665) 933569..933913 + 345 WP_142829512.1 cupin domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(13-92)

Antitoxin

(5-91)


Sequences


Toxin        


Download         Length: 97 a.a.        Molecular weight: 10727.40 Da        Isoelectric Point: 10.2980

>T270217 WP_142829519.1 NZ_CP117267:c929517-929227 [Rhizobium rhododendri]
VIEVRQTSIFANWLDALRDAQARQRIVVRIRRLELGNPGDIKPVGEGVSEMRIPHGPGYRLYFTRSGETIVILLCGGDKS
SQARDIAIARQLAKEI

Download         Length: 291 bp


Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10396.79 Da        Isoelectric Point: 4.4079

>AT270217 WP_142829521.1 NZ_CP117267:c929226-928930 [Rhizobium rhododendri]
MPLETTRFDIQDHLTTPADRMLYLEAAFEDGDPALITQALGDVARAAGMTSVAKEAGVTREALYKSLSEAGDPRLSTFLG
VIKALGLKVSISTDQNAA

Download         Length: 297 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References