Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-ChpS
Location 161794..162380 Replicon chromosome
Accession NZ_CP117267
Organism Rhizobium rhododendri strain rho-6.2

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag PR018_RS00820 Protein ID WP_142829131.1
Coordinates 162051..162380 (+) Length 110 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag PR018_RS00815 Protein ID WP_142823966.1
Coordinates 161794..162051 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PR018_RS00810 (PR018_00810) 159911..161707 + 1797 WP_142829129.1 acyl-CoA dehydrogenase C-terminal domain-containing protein -
PR018_RS00815 (PR018_00815) 161794..162051 + 258 WP_142823966.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
PR018_RS00820 (PR018_00820) 162051..162380 + 330 WP_142829131.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
PR018_RS00825 (PR018_00825) 162427..163635 + 1209 WP_142829133.1 acetyl-CoA C-acetyltransferase -
PR018_RS00830 (PR018_00830) 163726..165939 + 2214 WP_142823969.1 3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein -
PR018_RS00835 (PR018_00835) 166351..166692 - 342 WP_142823970.1 oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-109)

Antitoxin

Antitoxin PemI-like

(4-84)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 11975.84 Da        Isoelectric Point: 9.8009

>T270214 WP_142829131.1 NZ_CP117267:162051-162380 [Rhizobium rhododendri]
VDRGDIWHVDLEPIRGREQAGARYVLVVTKKSFNAIGTPIVVPITTGSEFARFKGFAVSLSGAGTRSSGVILCNQLRSLD
LRARGGKYVESVPDFIMFEVLARITIFFD

Download         Length: 330 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9296.57 Da        Isoelectric Point: 4.2457

>AT270214 WP_142823966.1 NZ_CP117267:161794-162051 [Rhizobium rhododendri]
MATSTLRNVGGSVMMTIPKAVVDELGLTANTKVEVLAEDGRVVAVPHKRPKYTLDELLAQCDLDAPFTEEDREWLDDAPS
GREVI

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References