270212

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 155501..156171 Replicon plasmid pRt932
Accession NZ_CP117262
Organism Rhizobium tumorigenes strain 932

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PR016_RS19370 Protein ID WP_278332953.1
Coordinates 155501..155920 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PR016_RS19375 Protein ID WP_111215819.1
Coordinates 155917..156171 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PR016_RS19350 (PR016_19350) 151989..153527 - 1539 WP_278332949.1 hypothetical protein -
PR016_RS19355 (PR016_19355) 153723..153914 + 192 WP_278332950.1 hypothetical protein -
PR016_RS19360 (PR016_19360) 154207..154785 + 579 WP_278332951.1 hypothetical protein -
PR016_RS19365 (PR016_19365) 154786..155352 + 567 WP_278332952.1 hypothetical protein -
PR016_RS19370 (PR016_19370) 155501..155920 - 420 WP_278332953.1 type II toxin-antitoxin system VapC family toxin Toxin
PR016_RS19375 (PR016_19375) 155917..156171 - 255 WP_111215819.1 plasmid stabilization protein Antitoxin
PR016_RS19380 (PR016_19380) 156631..157776 - 1146 WP_278332954.1 class C beta-lactamase -
PR016_RS19385 (PR016_19385) 158163..158816 - 654 WP_278332955.1 flavin reductase family protein -
PR016_RS19390 (PR016_19390) 158817..160238 - 1422 WP_278332956.1 Xaa-Pro peptidase family protein -
PR016_RS19395 (PR016_19395) 160277..161098 - 822 WP_278332957.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..756443 756443


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 14866.09 Da        Isoelectric Point: 5.1007

>T270212 WP_278332953.1 NZ_CP117262:c155920-155501 [Rhizobium tumorigenes]
MILLDTNVVSEPWKPAPDTAVLTWLDAQAIETLFISAISIAELRFGIASMPSGKRQTILHDRLEGEVLPIFDGRVLPFNV
GTAQFYAKLMASAQTSGKAIGKADGYIAATAAENHLAVATRDTSPFEAAGVRVINPWVA

Download         Length: 420 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9213.37 Da        Isoelectric Point: 7.3218

>AT270212 WP_111215819.1 NZ_CP117262:c156171-155917 [Rhizobium tumorigenes]
VAAVTIRNISDETHRALRARATHHGRSTEAEIRDILEAAVRPSGRVKLGSLLAAIGRDAKLSDSDVEALQQQRDRTPAEP
MIFE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References