Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 2705481..2706069 Replicon chromosome
Accession NZ_CP117261
Organism Rhizobium tumorigenes strain 932

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PR016_RS13315 Protein ID WP_278330333.1
Coordinates 2705481..2705786 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag PR016_RS13320 Protein ID WP_278330334.1
Coordinates 2705779..2706069 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PR016_RS13295 (PR016_13295) 2700731..2701522 + 792 WP_278330330.1 aldolase -
PR016_RS13300 (PR016_13300) 2701669..2702616 - 948 WP_278330331.1 substrate-binding domain-containing protein -
PR016_RS13305 (PR016_13305) 2702690..2703697 - 1008 WP_278332527.1 ABC transporter permease -
PR016_RS13310 (PR016_13310) 2703709..2705229 - 1521 WP_278330332.1 sugar ABC transporter ATP-binding protein -
PR016_RS13315 (PR016_13315) 2705481..2705786 + 306 WP_278330333.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PR016_RS13320 (PR016_13320) 2705779..2706069 + 291 WP_278330334.1 putative addiction module antidote protein Antitoxin
PR016_RS13325 (PR016_13325) 2706114..2707424 - 1311 WP_111218852.1 xylose isomerase -
PR016_RS13330 (PR016_13330) 2707538..2708992 - 1455 WP_278330335.1 xylulokinase -
PR016_RS13335 (PR016_13335) 2709017..2710042 - 1026 WP_278330336.1 LacI family DNA-binding transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Uncharacterized protein HI1420

(4-91)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11382.85 Da        Isoelectric Point: 9.9056

>T270211 WP_278330333.1 NZ_CP117261:2705481-2705786 [Rhizobium tumorigenes]
MLELRQTAAFAKWRQRLTDDRARAIIASRLDRLAYGHSGDAQSVGDGVQELRIQYGPGYRIYFKTRGNTLIILLCGSDKS
TQARDISAAKRLLTEWSDDHG

Download         Length: 306 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10144.61 Da        Isoelectric Point: 4.4000

>AT270211 WP_278330334.1 NZ_CP117261:2705779-2706069 [Rhizobium tumorigenes]
MVEKLTPYDPAEDLVSDEAMAVFMGEAFETGDAGYIAHALGVVARAKGMTQIATDTGLSREQLYRSFSEAGNPTLKTTMA
VMKALGITLTAKVAAE

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References