Detailed information of TA system TA270210

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /BrnT(toxin)
• Location: 2218136..2218580
• Replicon: chromosome
• Accession: NZ_CP117261
• Organism: Rhizobium tumorigenes strain 932

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: PR016_RS11065
• Protein ID: WP_278332510.1
• Coordinates: 2218365..2218580 (-)
• Length: 72 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: PR016_RS11060
• Protein ID: WP_278329992.1
• Coordinates: 2218136..2218378 (-)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PR016_RS11040 (PR016_11040)	2213390..2214298	+	909	WP_111222671.1	metallophosphoesterase	-
PR016_RS11045 (PR016_11045)	2214615..2215127	+	513	WP_278329989.1	RNA polymerase sigma factor	-
PR016_RS11050 (PR016_11050)	2215130..2215963	+	834	WP_278329990.1	anti-sigma factor	-
PR016_RS11055 (PR016_11055)	2216038..2217780	-	1743	WP_278329991.1	2-isopropylmalate synthase	-
PR016_RS11060 (PR016_11060)	2218136..2218378	-	243	WP_278329992.1	CopG family transcriptional regulator	Antitoxin
PR016_RS11065 (PR016_11065)	2218365..2218580	-	216	WP_278332510.1	BrnT family toxin	Toxin
PR016_RS11070 (PR016_11070)	2218666..2219856	-	1191	WP_278329993.1	benzoate/H(+) symporter BenE family transporter	-
PR016_RS11075 (PR016_11075)	2219956..2220690	-	735	WP_278329994.1	class I SAM-dependent methyltransferase	-
PR016_RS11080 (PR016_11080)	2220782..2221366	-	585	WP_111222663.1	ATP-dependent Clp protease proteolytic subunit	-
PR016_RS11085 (PR016_11085)	2221585..2222400	+	816	WP_278329995.1	DUF2076 domain-containing protein	-
PR016_RS11090 (PR016_11090)	2222464..2222928	-	465	WP_278329996.1	preQ(1) synthase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (9-64)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 72 a.a.
• Molecular weight: 8483.86 Da
• Isoelectric Point: 10.9766

>T270210 WP_278332510.1 NZ_CP117261:c2218580-2218365 [Rhizobium tumorigenes]
MVLILWRRSDLWIDRFLISFPARDGLESRFVAVGQIDGKHWSSICTRRHENIRIISVRRSRKEEIALYEGK

Nucleotide

• Length: 216 bp

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 9001.07 Da
• Isoelectric Point: 4.3193

>AT270210 WP_278329992.1 NZ_CP117261:c2218378-2218136 [Rhizobium tumorigenes]
MKASELDEKFDNGEDILDYLDLTKATRPNMATQKVSVDFATSVVNSLDEEAARLGLTRQSLINLWIEERLSAAQDQRKVS

Nucleotide

• Length: 243 bp