Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 3843551..3844086 Replicon chromosome
Accession NC_017564
Organism Yersinia enterocolitica subsp. palearctica Y11

Toxin (Protein)


Gene name relE Uniprot ID A0A7U7FI46
Locus tag Y11_RS17605 Protein ID WP_005156226.1
Coordinates 3843799..3844086 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7U7FI63
Locus tag Y11_RS17600 Protein ID WP_005156229.1
Coordinates 3843551..3843802 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Y11_RS17575 3838768..3839652 + 885 WP_005156239.1 sugar ABC transporter permease -
Y11_RS17580 3839671..3840510 + 840 WP_005156238.1 carbohydrate ABC transporter permease -
Y11_RS17585 3840522..3841637 + 1116 WP_005156237.1 ABC transporter ATP-binding protein -
Y11_RS17590 3841651..3842817 + 1167 WP_005156235.1 alginate lyase family protein -
Y11_RS17595 3842891..3843343 + 453 WP_005181269.1 YhbP family protein -
Y11_RS17600 3843551..3843802 + 252 WP_005156229.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
Y11_RS17605 3843799..3844086 + 288 WP_005156226.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
Y11_RS17610 3844162..3844791 + 630 WP_005175332.1 hypothetical protein -
Y11_RS17615 3844792..3845559 - 768 WP_005156220.1 phosphonate metabolism protein PhnP -
Y11_RS17620 3845550..3846127 - 578 Protein_3432 ribose 1,5-bisphosphokinase -
Y11_RS17625 3846127..3847275 - 1149 WP_005156213.1 alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase -
Y11_RS17630 3847272..3848006 - 735 WP_005156211.1 phosphonate C-P lyase system protein PhnL -
Y11_RS17635 3848020..3848826 - 807 WP_005156209.1 phosphonate C-P lyase system protein PhnK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11002.07 Da        Isoelectric Point: 10.3544

>T27021 WP_005156226.1 NC_017564:3843799-3844086 [Yersinia enterocolitica subsp. palearctica Y11]
MIYKVKFRSDALKEWGKIDKVIQQQFAKKLKKCCENPHIPSAKLRGLSDCYKIKLRASGFRLVYQVIEDCLVIAVVAVGK
RERSDVYNLASERLR

Download         Length: 288 bp

>T27021 NC_017564:3843799-3844086 [Yersinia enterocolitica subsp. palearctica Y11]
ATGATTTATAAAGTAAAATTTAGAAGTGATGCCCTAAAGGAATGGGGAAAGATAGACAAAGTTATTCAACAGCAGTTTGC
TAAAAAACTCAAAAAATGTTGTGAAAATCCTCATATTCCATCAGCAAAATTACGCGGATTATCAGACTGCTATAAAATAA
AATTACGGGCATCTGGTTTTAGGTTAGTTTATCAAGTTATTGAAGATTGTTTAGTTATCGCCGTGGTTGCCGTCGGCAAA
CGCGAACGCAGTGATGTTTATAACCTCGCCAGTGAACGGTTACGATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9270.65 Da        Isoelectric Point: 4.2264

>AT27021 WP_005156229.1 NC_017564:3843551-3843802 [Yersinia enterocolitica subsp. palearctica Y11]
MANIILSDTSASVSELKKNPMATVKAGAGYPVAILNRNQPAFYCIPAELYERMLDALDDQELIRLVTERESQPLIDVDLD
KYL

Download         Length: 252 bp

>AT27021 NC_017564:3843551-3843802 [Yersinia enterocolitica subsp. palearctica Y11]
ATGGCTAACATAATTTTAAGTGATACGAGCGCAAGTGTCAGCGAGTTAAAGAAAAACCCTATGGCCACAGTCAAAGCGGG
GGCGGGCTATCCAGTGGCTATTTTGAATAGAAACCAACCGGCATTTTATTGTATCCCCGCAGAATTATACGAGAGAATGC
TAGATGCCCTTGATGATCAAGAGCTTATCAGATTAGTTACCGAACGAGAGAGTCAGCCACTCATTGATGTAGATCTGGAT
AAGTATCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7U7FI46

Antitoxin

Source ID Structure
AlphaFold DB A0A7U7FI63

References