Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 1522386..1522990 Replicon chromosome
Accession NZ_CP117261
Organism Rhizobium tumorigenes strain 932

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PR016_RS07675 Protein ID WP_278332197.1
Coordinates 1522386..1522691 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PR016_RS07680 Protein ID WP_278332198.1
Coordinates 1522688..1522990 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PR016_RS07655 (PR016_07655) 1517822..1518184 + 363 WP_111221915.1 glycine cleavage system protein GcvH -
PR016_RS07660 (PR016_07660) 1518184..1521048 + 2865 WP_278332196.1 aminomethyl-transferring glycine dehydrogenase -
PR016_RS07665 (PR016_07665) 1521084..1521707 - 624 WP_111221913.1 LysE family transporter -
PR016_RS07670 (PR016_07670) 1521803..1522195 - 393 WP_111221912.1 Fe-S cluster assembly scaffold SufA -
PR016_RS07675 (PR016_07675) 1522386..1522691 + 306 WP_278332197.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PR016_RS07680 (PR016_07680) 1522688..1522990 + 303 WP_278332198.1 putative addiction module antidote protein Antitoxin
PR016_RS07685 (PR016_07685) 1522991..1523371 - 381 WP_209183816.1 SUF system Fe-S cluster assembly protein -
PR016_RS07690 (PR016_07690) 1523486..1524727 - 1242 WP_278332199.1 cysteine desulfurase -
PR016_RS07695 (PR016_07695) 1524740..1526014 - 1275 WP_278332200.1 Fe-S cluster assembly protein SufD -
PR016_RS07700 (PR016_07700) 1526037..1526792 - 756 WP_278332201.1 Fe-S cluster assembly ATPase SufC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-95)

Antitoxin

Uncharacterized protein HI1420

(5-89)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11860.75 Da        Isoelectric Point: 10.8426

>T270209 WP_278332197.1 NZ_CP117261:1522386-1522691 [Rhizobium tumorigenes]
VFVIQRTEIFQQWIMRLKDRRAAARIASRILRAEDGNLGDVKPVGDGVEEMRIDYGPGYRIYFLRRRSVLVVLLVGGDKS
TQRRDIIEAKRLCAEWRERNQ

Download         Length: 306 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10496.93 Da        Isoelectric Point: 4.5557

>AT270209 WP_278332198.1 NZ_CP117261:1522688-1522990 [Rhizobium tumorigenes]
MTSDTRLFDASEVLDNESAVDEFLAAAFETEDPAFIAKSLGVIAKTRNMSALARDVGMSRAALYKSLSGEGNPEFATIIK
VMKALGLGLAPVSRSNQGAA

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References