Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 970955..971542 Replicon chromosome
Accession NZ_CP117261
Organism Rhizobium tumorigenes strain 932

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PR016_RS04895 Protein ID WP_278332645.1
Coordinates 971252..971542 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PR016_RS04890 Protein ID WP_278331805.1
Coordinates 970955..971251 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PR016_RS04870 (PR016_04870) 966887..967840 + 954 WP_278332644.1 hypothetical protein -
PR016_RS04875 (PR016_04875) 967886..968677 - 792 WP_278331802.1 sulfite exporter TauE/SafE family protein -
PR016_RS04880 (PR016_04880) 968700..969632 - 933 WP_278331803.1 N-acetyl-gamma-glutamyl-phosphate reductase -
PR016_RS04885 (PR016_04885) 969715..970668 - 954 WP_278331804.1 agmatinase -
PR016_RS04890 (PR016_04890) 970955..971251 - 297 WP_278331805.1 putative addiction module antidote protein Antitoxin
PR016_RS04895 (PR016_04895) 971252..971542 - 291 WP_278332645.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PR016_RS04900 (PR016_04900) 971666..972136 - 471 WP_111220548.1 30S ribosomal protein S9 -
PR016_RS04905 (PR016_04905) 972139..972603 - 465 WP_111220549.1 50S ribosomal protein L13 -
PR016_RS04910 (PR016_04910) 973189..973515 - 327 WP_278331807.1 hypothetical protein -
PR016_RS04915 (PR016_04915) 973625..974056 + 432 WP_278331808.1 CoA-binding protein -
PR016_RS04920 (PR016_04920) 974175..975458 + 1284 WP_278331809.1 O-acetylhomoserine aminocarboxypropyltransferase -
PR016_RS04925 (PR016_04925) 975585..975929 + 345 WP_111220553.1 cupin domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-92)

Antitoxin

Uncharacterized protein HI1420

(5-91)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10653.37 Da        Isoelectric Point: 10.6628

>T270208 WP_278332645.1 NZ_CP117261:c971542-971252 [Rhizobium tumorigenes]
VIEVRQTAIFANWLDALRDAQARQRIVVRIRRLELGNPGDIKPVGEGVSEMRIPHGPGYRLYFTRSGATIVILLCGGDKS
SQARDIAIARQLAKEI

Download         Length: 291 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10271.66 Da        Isoelectric Point: 4.4067

>AT270208 WP_278331805.1 NZ_CP117261:c971251-970955 [Rhizobium tumorigenes]
MPLETTHFDIQDHLATPADRMLYLEAAFEDGDPALIAQALGDVARAAGMTSVAKEAGVTREALYKSLSEAGDPRLSTFLG
VIKALGLKVSIAADQNAA

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References