Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/HTH_26(antitoxin) |
| Location | 621250..621864 | Replicon | chromosome |
| Accession | NZ_CP117261 | ||
| Organism | Rhizobium tumorigenes strain 932 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | PR016_RS03110 | Protein ID | WP_111220170.1 |
| Coordinates | 621250..621495 (+) | Length | 82 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | PR016_RS03115 | Protein ID | WP_111220171.1 |
| Coordinates | 621502..621864 (+) | Length | 121 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PR016_RS03085 (PR016_03085) | 616500..617867 | - | 1368 | WP_278331542.1 | chloride channel protein | - |
| PR016_RS03090 (PR016_03090) | 618051..618326 | + | 276 | WP_278331543.1 | YlcI/YnfO family protein | - |
| PR016_RS03095 (PR016_03095) | 618323..618622 | + | 300 | WP_278331544.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| PR016_RS03100 (PR016_03100) | 618811..619299 | + | 489 | WP_278331545.1 | GNAT family N-acetyltransferase | - |
| PR016_RS03105 (PR016_03105) | 619504..621156 | - | 1653 | WP_278331546.1 | choline dehydrogenase | - |
| PR016_RS03110 (PR016_03110) | 621250..621495 | + | 246 | WP_111220170.1 | cytotoxic translational repressor of toxin-antitoxin stability system | Toxin |
| PR016_RS03115 (PR016_03115) | 621502..621864 | + | 363 | WP_111220171.1 | helix-turn-helix transcriptional regulator | Antitoxin |
| PR016_RS03120 (PR016_03120) | 621876..623339 | - | 1464 | WP_278331547.1 | betaine-aldehyde dehydrogenase | - |
| PR016_RS03125 (PR016_03125) | 623341..624870 | - | 1530 | WP_278331548.1 | choline-sulfatase | - |
| PR016_RS03130 (PR016_03130) | 624867..625466 | - | 600 | WP_278331549.1 | transcriptional regulator BetI | - |
| PR016_RS03135 (PR016_03135) | 625637..626185 | + | 549 | WP_278332622.1 | HdeD family acid-resistance protein | - |
| PR016_RS03140 (PR016_03140) | 626377..626631 | + | 255 | WP_278331550.1 | type II toxin-antitoxin system ParD family antitoxin | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 82 a.a. Molecular weight: 9237.06 Da Isoelectric Point: 11.0766
>T270207 WP_111220170.1 NZ_CP117261:621250-621495 [Rhizobium tumorigenes]
MRDVVVSRLADKALMRMQPKRRLAIIEKVKAYARGEIVDIKKMKGGNLYRIRVGQDRVIIDDKGRIVVVIDAGPRGSIYK
E
MRDVVVSRLADKALMRMQPKRRLAIIEKVKAYARGEIVDIKKMKGGNLYRIRVGQDRVIIDDKGRIVVVIDAGPRGSIYK
E
Download Length: 246 bp
Antitoxin
Download Length: 121 a.a. Molecular weight: 13054.78 Da Isoelectric Point: 4.2616
>AT270207 WP_111220171.1 NZ_CP117261:621502-621864 [Rhizobium tumorigenes]
MGDIKRFEIDGKPYVLLSEEDYEDLVDGLRANAVLAGISAGEETWPLEIVEARANGGNAVRIFRNYRRMTVTELATAAGI
SQPYLSEIEAGKKTGSVDVLKRIATALKVDLDDLVVDVAD
MGDIKRFEIDGKPYVLLSEEDYEDLVDGLRANAVLAGISAGEETWPLEIVEARANGGNAVRIFRNYRRMTVTELATAAGI
SQPYLSEIEAGKKTGSVDVLKRIATALKVDLDDLVVDVAD
Download Length: 363 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|