Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/HTH_26(antitoxin)
Location 621250..621864 Replicon chromosome
Accession NZ_CP117261
Organism Rhizobium tumorigenes strain 932

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PR016_RS03110 Protein ID WP_111220170.1
Coordinates 621250..621495 (+) Length 82 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PR016_RS03115 Protein ID WP_111220171.1
Coordinates 621502..621864 (+) Length 121 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PR016_RS03085 (PR016_03085) 616500..617867 - 1368 WP_278331542.1 chloride channel protein -
PR016_RS03090 (PR016_03090) 618051..618326 + 276 WP_278331543.1 YlcI/YnfO family protein -
PR016_RS03095 (PR016_03095) 618323..618622 + 300 WP_278331544.1 type II toxin-antitoxin system RelE/ParE family toxin -
PR016_RS03100 (PR016_03100) 618811..619299 + 489 WP_278331545.1 GNAT family N-acetyltransferase -
PR016_RS03105 (PR016_03105) 619504..621156 - 1653 WP_278331546.1 choline dehydrogenase -
PR016_RS03110 (PR016_03110) 621250..621495 + 246 WP_111220170.1 cytotoxic translational repressor of toxin-antitoxin stability system Toxin
PR016_RS03115 (PR016_03115) 621502..621864 + 363 WP_111220171.1 helix-turn-helix transcriptional regulator Antitoxin
PR016_RS03120 (PR016_03120) 621876..623339 - 1464 WP_278331547.1 betaine-aldehyde dehydrogenase -
PR016_RS03125 (PR016_03125) 623341..624870 - 1530 WP_278331548.1 choline-sulfatase -
PR016_RS03130 (PR016_03130) 624867..625466 - 600 WP_278331549.1 transcriptional regulator BetI -
PR016_RS03135 (PR016_03135) 625637..626185 + 549 WP_278332622.1 HdeD family acid-resistance protein -
PR016_RS03140 (PR016_03140) 626377..626631 + 255 WP_278331550.1 type II toxin-antitoxin system ParD family antitoxin -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

(67-114)


Sequences


Toxin        


Download         Length: 82 a.a.        Molecular weight: 9237.06 Da        Isoelectric Point: 11.0766

>T270207 WP_111220170.1 NZ_CP117261:621250-621495 [Rhizobium tumorigenes]
MRDVVVSRLADKALMRMQPKRRLAIIEKVKAYARGEIVDIKKMKGGNLYRIRVGQDRVIIDDKGRIVVVIDAGPRGSIYK
E

Download         Length: 246 bp


Antitoxin


Download         Length: 121 a.a.        Molecular weight: 13054.78 Da        Isoelectric Point: 4.2616

>AT270207 WP_111220171.1 NZ_CP117261:621502-621864 [Rhizobium tumorigenes]
MGDIKRFEIDGKPYVLLSEEDYEDLVDGLRANAVLAGISAGEETWPLEIVEARANGGNAVRIFRNYRRMTVTELATAAGI
SQPYLSEIEAGKKTGSVDVLKRIATALKVDLDDLVVDVAD

Download         Length: 363 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References