270204

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 398454..399088 Replicon chromosome
Accession NZ_CP117261
Organism Rhizobium tumorigenes strain 932

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PR016_RS01950 Protein ID WP_111217666.1
Coordinates 398681..399088 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PR016_RS01945 Protein ID WP_278331353.1
Coordinates 398454..398684 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PR016_RS01925 (PR016_01925) 394386..394997 + 612 WP_278331352.1 hypothetical protein -
PR016_RS01930 (PR016_01930) 395301..397106 + 1806 WP_161959296.1 DUF3857 domain-containing protein -
PR016_RS01935 (PR016_01935) 397317..398180 + 864 WP_111217660.1 S49 family peptidase -
PR016_RS01940 (PR016_01940) 398199..398390 + 192 WP_111217662.1 hypothetical protein -
PR016_RS01945 (PR016_01945) 398454..398684 + 231 WP_278331353.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
PR016_RS01950 (PR016_01950) 398681..399088 + 408 WP_111217666.1 PIN domain-containing protein Toxin
PR016_RS01955 (PR016_01955) 399177..400136 + 960 WP_278331354.1 glycine--tRNA ligase subunit alpha -
PR016_RS01960 (PR016_01960) 400231..400782 + 552 WP_278331356.1 LemA family protein -
PR016_RS01965 (PR016_01965) 400878..402152 + 1275 WP_278331357.1 3-phosphoshikimate 1-carboxyvinyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-117)

Antitoxin

SpoVT-AbrB domain

(5-39)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 14773.01 Da        Isoelectric Point: 5.0344

>T270204 WP_111217666.1 NZ_CP117261:398681-399088 [Rhizobium tumorigenes]
VTTAATNFLDTNILIYAISDDRRAIQAQALLDLPFVVSGQTLNEFANVARKKLSMSWQDTSTAIEAIVSISTLVVPVDEK
VTLAALKLAPLYNLSFYDAAMIAAALQAGCKQYYSEDMQHGLVVEKHLTIVNPFH

Download         Length: 408 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8610.76 Da        Isoelectric Point: 6.3255

>AT270204 WP_278331353.1 NZ_CP117261:398454-398684 [Rhizobium tumorigenes]
MQVAKWGNSLAIRIPSSVVDALDLKEGDDISVSISNDRAVEIERDDRRLKALERIKSFGVKLPVDWKFDRNDANAR

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References