270203

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) BrnTA/BrnT-BrnA
Location 330930..331482 Replicon chromosome
Accession NZ_CP117261
Organism Rhizobium tumorigenes strain 932

Toxin (Protein)


Gene name brnT Uniprot ID -
Locus tag PR016_RS01625 Protein ID WP_278332608.1
Coordinates 331222..331482 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID -
Locus tag PR016_RS01620 Protein ID WP_278331311.1
Coordinates 330930..331238 (-) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PR016_RS01590 (PR016_01590) 326598..327227 + 630 WP_278331305.1 DNA-3-methyladenine glycosylase I -
PR016_RS01595 (PR016_01595) 327320..327790 + 471 WP_142824459.1 hypothetical protein -
PR016_RS01600 (PR016_01600) 327802..328512 - 711 WP_278331306.1 HAD family hydrolase -
PR016_RS01605 (PR016_01605) 328747..329793 + 1047 WP_278331307.1 aldo/keto reductase -
PR016_RS01610 (PR016_01610) 329841..330470 - 630 WP_278331308.1 phosphoribosyltransferase family protein -
PR016_RS01615 (PR016_01615) 330519..330881 - 363 WP_278331309.1 DUF305 domain-containing protein -
PR016_RS01620 (PR016_01620) 330930..331238 - 309 WP_278331311.1 BrnA antitoxin family protein Antitoxin
PR016_RS01625 (PR016_01625) 331222..331482 - 261 WP_278332608.1 BrnT family toxin Toxin
PR016_RS01630 (PR016_01630) 331551..332321 - 771 WP_278331312.1 hypothetical protein -
PR016_RS01635 (PR016_01635) 332551..334176 + 1626 WP_278331313.1 histidine--tRNA ligase -
PR016_RS01640 (PR016_01640) 334208..335329 + 1122 WP_278331314.1 ATP phosphoribosyltransferase regulatory subunit -
PR016_RS01645 (PR016_01645) 335326..336027 + 702 WP_278331315.1 ATP phosphoribosyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-77)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(27-100)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9719.26 Da        Isoelectric Point: 10.3839

>T270203 WP_278332608.1 NZ_CP117261:c331482-331222 [Rhizobium tumorigenes]
MKITWDERKRLANFDKHGLDFAELDADFFLAALLQPAKLGRFKAIGRRHDGTIAVIFAVLGREAVSVISMRPAHKAERSL
LNDKEN

Download         Length: 261 bp

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11784.14 Da        Isoelectric Point: 5.3048

>AT270203 WP_278331311.1 NZ_CP117261:c331238-330930 [Rhizobium tumorigenes]
MTKKTEMRSDFQDGRGYSEQDWEEVSDNPEWTEEDFKNARPFAEVFPDLAESIRRARGRPAVEAPKRQISLRLDPDVIDA
FKATGKGWQSRINEALRKAAKI

Download         Length: 309 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References