Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-MazE
Location 159856..160445 Replicon chromosome
Accession NZ_CP117261
Organism Rhizobium tumorigenes strain 932

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag PR016_RS00800 Protein ID WP_111216718.1
Coordinates 160116..160445 (+) Length 110 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag PR016_RS00795 Protein ID WP_278331203.1
Coordinates 159856..160116 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PR016_RS00790 (PR016_00790) 157998..159794 + 1797 WP_278331202.1 acyl-CoA dehydrogenase C-terminal domain-containing protein -
PR016_RS00795 (PR016_00795) 159856..160116 + 261 WP_278331203.1 antitoxin Antitoxin
PR016_RS00800 (PR016_00800) 160116..160445 + 330 WP_111216718.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
PR016_RS00805 (PR016_00805) 160487..161695 + 1209 WP_278331204.1 acetyl-CoA C-acetyltransferase -
PR016_RS00810 (PR016_00810) 161698..162081 + 384 WP_278331205.1 cupin domain-containing protein -
PR016_RS00815 (PR016_00815) 162097..164307 + 2211 WP_278331206.1 3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein -
PR016_RS00820 (PR016_00820) 164687..165151 - 465 WP_278331207.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-108)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 11956.69 Da        Isoelectric Point: 9.1988

>T270202 WP_111216718.1 NZ_CP117261:160116-160445 [Rhizobium tumorigenes]
MERGEIWFVDLEPTRGREQANERYAMILSPKVVNQHGTQIVAPITTGGQFARTSGFAVSLSGAGTRSTGVVLCHQIRAVD
IKARRGRFVEKAPDFIVDEVLARVAALFD

Download         Length: 330 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9642.97 Da        Isoelectric Point: 4.3219

>AT270202 WP_278331203.1 NZ_CP117261:159856-160116 [Rhizobium tumorigenes]
MVASTLRNVGGSLVMTVPKAITDELGLHANTKFDVIAQDGNIIAVPRRRPKYTVEQLVAEWEVWPERTAEEQEWLDIPSV
GNEIIE

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References