Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 747486..748171 Replicon plasmid pRt1078
Accession NZ_CP117256
Organism Rhizobium tumorigenes strain 1078

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PR017_RS21205 Protein ID WP_111217068.1
Coordinates 747749..748171 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PR017_RS21200 Protein ID WP_111217148.1
Coordinates 747486..747752 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PR017_RS21180 (PR017_21180) 744029..744202 + 174 WP_206423114.1 hypothetical protein -
PR017_RS21185 (PR017_21185) 744151..745228 + 1078 Protein_685 IS630 family transposase -
PR017_RS21190 (PR017_21190) 745254..745403 + 150 WP_161959286.1 methyltransferase domain-containing protein -
PR017_RS21195 (PR017_21195) 745567..745866 + 300 WP_111217072.1 hypothetical protein -
PR017_RS21200 (PR017_21200) 747486..747752 + 267 WP_111217148.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PR017_RS21205 (PR017_21205) 747749..748171 + 423 WP_111217068.1 type II toxin-antitoxin system VapC family toxin Toxin
PR017_RS21210 (PR017_21210) 748208..748771 + 564 WP_111217066.1 hypothetical protein -
PR017_RS21215 (PR017_21215) 749219..749542 + 324 WP_111217064.1 hypothetical protein -
PR017_RS21220 (PR017_21220) 750199..750627 - 429 WP_111217061.1 MucR family transcriptional regulator -
PR017_RS21225 (PR017_21225) 751236..752006 + 771 WP_111217059.1 SDR family NAD(P)-dependent oxidoreductase -
PR017_RS21230 (PR017_21230) 752237..753046 + 810 WP_111217057.1 mechanosensitive ion channel -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..834411 834411
- flank IS/Tn - - 744151..744951 800


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-125)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-72)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15562.99 Da        Isoelectric Point: 5.6638

>T270200 WP_111217068.1 NZ_CP117256:747749-748171 [Rhizobium tumorigenes]
MRLLLDTNVLSEVTKLRPTERVLNWLHGLDEDRTFISIVSIAEIRRGVALMEIGRKRDALDAWLTHDLPQRFENRIIPVD
GHVTLAWGDLMALAKQSGRGLASMDGLIAATAVACNLTLATRNTKDFEGFGIDLVDPWAV

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9751.99 Da        Isoelectric Point: 7.0166

>AT270200 WP_111217148.1 NZ_CP117256:747486-747752 [Rhizobium tumorigenes]
MRASTHDDMSWTVAGAKARLSEVMERAQSAPQTITRNGKPSVVVVSAEEWEKKTARRGSLAEFLLASPLRGADLDTERLR
DEPRDLSL

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References