Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 145380..146050 Replicon plasmid pRt1078
Accession NZ_CP117256
Organism Rhizobium tumorigenes strain 1078

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PR017_RS18460 Protein ID WP_111215811.1
Coordinates 145380..145799 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PR017_RS18465 Protein ID WP_111215819.1
Coordinates 145796..146050 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PR017_RS18435 (PR017_18435) 140426..140626 + 201 WP_111215818.1 type II toxin-antitoxin system VapB family antitoxin -
PR017_RS18440 (PR017_18440) 140623..141006 + 384 WP_111215816.1 type II toxin-antitoxin system VapC family toxin -
PR017_RS18445 (PR017_18445) 142034..142861 - 828 WP_111215821.1 SDR family oxidoreductase -
PR017_RS18450 (PR017_18450) 142885..144078 - 1194 WP_111215815.1 phytanoyl-CoA dioxygenase family protein -
PR017_RS18455 (PR017_18455) 144178..145194 + 1017 WP_240538814.1 LacI family DNA-binding transcriptional regulator -
PR017_RS18460 (PR017_18460) 145380..145799 - 420 WP_111215811.1 type II toxin-antitoxin system VapC family toxin Toxin
PR017_RS18465 (PR017_18465) 145796..146050 - 255 WP_111215819.1 plasmid stabilization protein Antitoxin
PR017_RS18470 (PR017_18470) 146218..146981 + 764 WP_111215810.1 IS5 family transposase -
PR017_RS18475 (PR017_18475) 147118..148344 - 1227 WP_111219125.1 IS701 family transposase -
PR017_RS18480 (PR017_18480) 148643..148906 + 264 WP_111215804.1 type II toxin-antitoxin system RelE/ParE family toxin -
PR017_RS18485 (PR017_18485) 148944..149258 + 315 WP_111215803.1 putative addiction module antidote protein -
PR017_RS18490 (PR017_18490) 149527..150315 - 789 WP_240538813.1 transporter substrate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..834411 834411


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 14834.11 Da        Isoelectric Point: 5.6982

>T270197 WP_111215811.1 NZ_CP117256:c145799-145380 [Rhizobium tumorigenes]
MILLDTNVVSEPWKPAPDTAVLTWLDAQAIETLFISAISIAELRFGIASMPSGKRQTILHDRLEGEVLPIFDGRVLPFNV
GTAQFYAKLMASARTSGKAIGKADGCIAATAAENHLAVATRDTSPFEAAGVRVINPWVA

Download         Length: 420 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9213.37 Da        Isoelectric Point: 7.3218

>AT270197 WP_111215819.1 NZ_CP117256:c146050-145796 [Rhizobium tumorigenes]
VAAVTIRNISDETHRALRARATHHGRSTEAEIRDILEAAVRPSGRVKLGSLLAAIGRDAKLSDSDVEALQQQRDRTPAEP
MIFE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References