Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 140426..141006 Replicon plasmid pRt1078
Accession NZ_CP117256
Organism Rhizobium tumorigenes strain 1078

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PR017_RS18440 Protein ID WP_111215816.1
Coordinates 140623..141006 (+) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PR017_RS18435 Protein ID WP_111215818.1
Coordinates 140426..140626 (+) Length 67 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PR017_RS18410 (PR017_18410) 136097..137122 + 1026 WP_111218184.1 IS110 family transposase -
PR017_RS18415 (PR017_18415) 137416..137786 - 371 Protein_131 transposase -
PR017_RS18425 (PR017_18425) 139071..139418 - 348 Protein_133 transposase -
PR017_RS18430 (PR017_18430) 139477..139920 - 444 WP_240538815.1 alpha/beta hydrolase fold domain-containing protein -
PR017_RS18435 (PR017_18435) 140426..140626 + 201 WP_111215818.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
PR017_RS18440 (PR017_18440) 140623..141006 + 384 WP_111215816.1 type II toxin-antitoxin system VapC family toxin Toxin
PR017_RS18445 (PR017_18445) 142034..142861 - 828 WP_111215821.1 SDR family oxidoreductase -
PR017_RS18450 (PR017_18450) 142885..144078 - 1194 WP_111215815.1 phytanoyl-CoA dioxygenase family protein -
PR017_RS18455 (PR017_18455) 144178..145194 + 1017 WP_240538814.1 LacI family DNA-binding transcriptional regulator -
PR017_RS18460 (PR017_18460) 145380..145799 - 420 WP_111215811.1 type II toxin-antitoxin system VapC family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..834411 834411


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-112)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-42)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14064.29 Da        Isoelectric Point: 7.0612

>T270196 WP_111215816.1 NZ_CP117256:140623-141006 [Rhizobium tumorigenes]
VILVDTSIWIDHFRHSDADLRKVIADDRLLCHPVVIGELALGSLRDRGVVMAFFSAQREALVASHDEVMTMIDRHSIFSM
GIGYTDAHLLASTLLDRRLLLWTRDKRLAAAAQKAGASLYAPTIAPN

Download         Length: 384 bp

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7098.10 Da        Isoelectric Point: 10.4525

>AT270196 WP_111215818.1 NZ_CP117256:140426-140626 [Rhizobium tumorigenes]
MRSTINLDDSLMEQARSLTGTKETAALVRQALETLVRVESGKRLAALGGTMPDAEAAPRRRSEAAK

Download         Length: 201 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References