Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 1467214..1467818 Replicon chromosome
Accession NZ_CP117255
Organism Rhizobium tumorigenes strain 1078

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PR017_RS07335 Protein ID WP_111221911.1
Coordinates 1467214..1467519 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PR017_RS07340 Protein ID WP_111221910.1
Coordinates 1467516..1467818 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PR017_RS07315 (PR017_07315) 1462650..1463012 + 363 WP_111221915.1 glycine cleavage system protein GcvH -
PR017_RS07320 (PR017_07320) 1463012..1465876 + 2865 WP_111221914.1 aminomethyl-transferring glycine dehydrogenase -
PR017_RS07325 (PR017_07325) 1465912..1466535 - 624 WP_111221913.1 LysE family transporter -
PR017_RS07330 (PR017_07330) 1466631..1467023 - 393 WP_111221912.1 Fe-S cluster assembly scaffold SufA -
PR017_RS07335 (PR017_07335) 1467214..1467519 + 306 WP_111221911.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PR017_RS07340 (PR017_07340) 1467516..1467818 + 303 WP_111221910.1 putative addiction module antidote protein Antitoxin
PR017_RS07345 (PR017_07345) 1467819..1468199 - 381 WP_111221909.1 SUF system Fe-S cluster assembly protein -
PR017_RS07350 (PR017_07350) 1468314..1469555 - 1242 WP_111222002.1 cysteine desulfurase -
PR017_RS07355 (PR017_07355) 1469568..1470842 - 1275 WP_111221908.1 Fe-S cluster assembly protein SufD -
PR017_RS07360 (PR017_07360) 1470865..1471620 - 756 WP_111221907.1 Fe-S cluster assembly ATPase SufC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-96)

Antitoxin

Cro/C1-type helix-turn-helix domain

(48-90)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11806.74 Da        Isoelectric Point: 10.8373

>T270193 WP_111221911.1 NZ_CP117255:1467214-1467519 [Rhizobium tumorigenes]
VFVIQRTEIFQQWIMRLKDRRAAARIASRILRAEDGNLGDVKAVGDGVEEMRIDYGPGYRIYFLRRRSVLVVLLVGGDKS
TQRRDIIEAKRLCAEWKERNK

Download         Length: 306 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10480.02 Da        Isoelectric Point: 4.5557

>AT270193 WP_111221910.1 NZ_CP117255:1467516-1467818 [Rhizobium tumorigenes]
MILDTKLFDASEVLDSESAVDEFLAAAFETEDPAFIAKSLGVIAKTRNMSALARDVGMSRAALYKSLSGEGNPEFATIIK
VMKALGLGLAPVSRSNQGAA

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References