Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 973436..974023 Replicon chromosome
Accession NZ_CP117255
Organism Rhizobium tumorigenes strain 1078

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PR017_RS04825 Protein ID WP_111220547.1
Coordinates 973733..974023 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PR017_RS04820 Protein ID WP_111220546.1
Coordinates 973436..973732 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PR017_RS04800 (PR017_04800) 969362..970315 + 954 WP_240539013.1 murein L,D-transpeptidase catalytic domain family protein -
PR017_RS04805 (PR017_04805) 970361..971152 - 792 WP_111220544.1 sulfite exporter TauE/SafE family protein -
PR017_RS04810 (PR017_04810) 971175..972107 - 933 WP_111220545.1 N-acetyl-gamma-glutamyl-phosphate reductase -
PR017_RS04815 (PR017_04815) 972190..973143 - 954 WP_111220801.1 agmatinase -
PR017_RS04820 (PR017_04820) 973436..973732 - 297 WP_111220546.1 putative addiction module antidote protein Antitoxin
PR017_RS04825 (PR017_04825) 973733..974023 - 291 WP_111220547.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PR017_RS04830 (PR017_04830) 974148..974618 - 471 WP_111220548.1 30S ribosomal protein S9 -
PR017_RS04835 (PR017_04835) 974621..975085 - 465 WP_111220549.1 50S ribosomal protein L13 -
PR017_RS04840 (PR017_04840) 975674..976000 - 327 WP_111220550.1 hypothetical protein -
PR017_RS04845 (PR017_04845) 976110..976541 + 432 WP_111220551.1 CoA-binding protein -
PR017_RS04850 (PR017_04850) 976660..977943 + 1284 WP_111220552.1 O-acetylhomoserine aminocarboxypropyltransferase -
PR017_RS04855 (PR017_04855) 978070..978414 + 345 WP_111220553.1 cupin domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-92)

Antitoxin

Uncharacterized protein HI1420

(4-95)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10717.43 Da        Isoelectric Point: 10.2980

>T270192 WP_111220547.1 NZ_CP117255:c974023-973733 [Rhizobium tumorigenes]
VIEVRQTAIFANWLDALRDAQARQRIVVRIRRLELGNPGDIKPVGEGVSEMRITHGPGYRLYFTRSGDMIVVLLCGGDKS
SQARDIAIARQLAKEI

Download         Length: 291 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10295.79 Da        Isoelectric Point: 4.5388

>AT270192 WP_111220546.1 NZ_CP117255:c973732-973436 [Rhizobium tumorigenes]
MPLETTRFDVLDHLTTPADRMLYLEAAFEDGAPALIAQALGDVARAAGMTSVAKEAGMTREALYKSLSEAGDPRLSTFLG
VIKALGLKVSISADQNAA

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References