Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 832629..833245 Replicon chromosome
Accession NZ_CP117255
Organism Rhizobium tumorigenes strain 1078

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PR017_RS04095 Protein ID WP_111220785.1
Coordinates 832943..833245 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag PR017_RS04090 Protein ID WP_111220422.1
Coordinates 832629..832946 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PR017_RS04050 (PR017_04050) 827676..828482 - 807 WP_111220414.1 mechanosensitive ion channel -
PR017_RS04055 (PR017_04055) 828542..829066 - 525 WP_111220415.1 tyrosine phosphatase family protein -
PR017_RS04060 (PR017_04060) 829063..829683 - 621 WP_111220416.1 HD family hydrolase -
PR017_RS04065 (PR017_04065) 829680..830519 - 840 WP_111220417.1 folate-binding protein YgfZ -
PR017_RS04070 (PR017_04070) 830598..831347 - 750 WP_111220418.1 hypothetical protein -
PR017_RS04075 (PR017_04075) 831364..831621 - 258 WP_142829924.1 hypothetical protein -
PR017_RS04080 (PR017_04080) 831731..832156 - 426 WP_111220420.1 TIGR02301 family protein -
PR017_RS04085 (PR017_04085) 832216..832632 - 417 WP_111220421.1 NUDIX domain-containing protein -
PR017_RS04090 (PR017_04090) 832629..832946 - 318 WP_111220422.1 putative addiction module antidote protein Antitoxin
PR017_RS04095 (PR017_04095) 832943..833245 - 303 WP_111220785.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PR017_RS04100 (PR017_04100) 833314..833634 + 321 WP_111220786.1 YnfA family protein -
PR017_RS04105 (PR017_04105) 833677..834441 + 765 WP_111220423.1 SOS response-associated peptidase -
PR017_RS04110 (PR017_04110) 834474..835085 + 612 WP_111220424.1 LysE/ArgO family amino acid transporter -
PR017_RS04115 (PR017_04115) 835082..835222 - 141 WP_164498240.1 hypothetical protein -
PR017_RS04120 (PR017_04120) 835485..836345 - 861 WP_111220425.1 CDP-diacylglycerol--serine O-phosphatidyltransferase -
PR017_RS04125 (PR017_04125) 836367..837065 - 699 WP_111220426.1 phosphatidylserine decarboxylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-94)

Antitoxin

Uncharacterized protein HI1420

(3-95)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11205.86 Da        Isoelectric Point: 10.2349

>T270191 WP_111220785.1 NZ_CP117255:c833245-832943 [Rhizobium tumorigenes]
VIEIRETEVYAGWFSRLRDERAKARINARIFRLANGNAGGHKSLGNSVLALRIDYGPGYRVYYTMLESVVVLLLCGGDKS
SQVDDITKARTLAEAARKFR

Download         Length: 303 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11167.80 Da        Isoelectric Point: 4.5482

>AT270191 WP_111220422.1 NZ_CP117255:c832946-832629 [Rhizobium tumorigenes]
MTLKTEKWDVSRHLDTDEKIALFLEAIFEEADAATIAAALGEVARAKGMSKVAEDAGLSKEGLDSALSGNGSPEFGTILR
VIKAVGFDLRVKPQVTPMPEINVAP

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References