Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/HTH_26(antitoxin)
Location 606833..607447 Replicon chromosome
Accession NZ_CP117255
Organism Rhizobium tumorigenes strain 1078

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PR017_RS02955 Protein ID WP_111220170.1
Coordinates 606833..607078 (+) Length 82 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PR017_RS02960 Protein ID WP_111220171.1
Coordinates 607085..607447 (+) Length 121 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PR017_RS02940 (PR017_02940) 602067..603434 - 1368 WP_111220162.1 chloride channel protein -
PR017_RS02945 (PR017_02945) 604001..605059 + 1059 WP_111220166.1 LacI family DNA-binding transcriptional regulator -
PR017_RS02950 (PR017_02950) 605087..606739 - 1653 WP_111220168.1 choline dehydrogenase -
PR017_RS02955 (PR017_02955) 606833..607078 + 246 WP_111220170.1 cytotoxic translational repressor of toxin-antitoxin stability system Toxin
PR017_RS02960 (PR017_02960) 607085..607447 + 363 WP_111220171.1 helix-turn-helix transcriptional regulator Antitoxin
PR017_RS02965 (PR017_02965) 607459..608922 - 1464 WP_111220173.1 betaine-aldehyde dehydrogenase -
PR017_RS02970 (PR017_02970) 608924..610453 - 1530 WP_111220175.1 choline-sulfatase -
PR017_RS02975 (PR017_02975) 610450..611049 - 600 WP_111220177.1 transcriptional regulator BetI -
PR017_RS02980 (PR017_02980) 611220..611768 + 549 WP_111220179.1 HdeD family acid-resistance protein -
PR017_RS02985 (PR017_02985) 611958..612212 + 255 WP_111220181.1 type II toxin-antitoxin system ParD family antitoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(67-114)


Sequences

Toxin        


Download         Length: 82 a.a.        Molecular weight: 9237.06 Da        Isoelectric Point: 11.0766

>T270190 WP_111220170.1 NZ_CP117255:606833-607078 [Rhizobium tumorigenes]
MRDVVVSRLADKALMRMQPKRRLAIIEKVKAYARGEIVDIKKMKGGNLYRIRVGQDRVIIDDKGRIVVVIDAGPRGSIYK
E

Download         Length: 246 bp

Antitoxin


Download         Length: 121 a.a.        Molecular weight: 13054.78 Da        Isoelectric Point: 4.2616

>AT270190 WP_111220171.1 NZ_CP117255:607085-607447 [Rhizobium tumorigenes]
MGDIKRFEIDGKPYVLLSEEDYEDLVDGLRANAVLAGISAGEETWPLEIVEARANGGNAVRIFRNYRRMTVTELATAAGI
SQPYLSEIEAGKKTGSVDVLKRIATALKVDLDDLVVDVAD

Download         Length: 363 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References