Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 422697..423331 Replicon chromosome
Accession NZ_CP117255
Organism Rhizobium tumorigenes strain 1078

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PR017_RS02095 Protein ID WP_111217666.1
Coordinates 422924..423331 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PR017_RS02090 Protein ID WP_111217664.1
Coordinates 422697..422927 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PR017_RS02070 (PR017_02070) 418629..419240 + 612 WP_133255555.1 hypothetical protein -
PR017_RS02075 (PR017_02075) 419544..421349 + 1806 WP_161959296.1 DUF3857 domain-containing protein -
PR017_RS02080 (PR017_02080) 421560..422423 + 864 WP_111217660.1 S49 family peptidase -
PR017_RS02085 (PR017_02085) 422442..422633 + 192 WP_111217662.1 hypothetical protein -
PR017_RS02090 (PR017_02090) 422697..422927 + 231 WP_111217664.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
PR017_RS02095 (PR017_02095) 422924..423331 + 408 WP_111217666.1 PIN domain-containing protein Toxin
PR017_RS02100 (PR017_02100) 423420..424379 + 960 WP_111217917.1 glycine--tRNA ligase subunit alpha -
PR017_RS02105 (PR017_02105) 424474..425025 + 552 WP_111217668.1 LemA family protein -
PR017_RS02110 (PR017_02110) 425122..426396 + 1275 WP_111217670.1 3-phosphoshikimate 1-carboxyvinyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-117)

Antitoxin

SpoVT-AbrB domain

(5-39)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 14773.01 Da        Isoelectric Point: 5.0344

>T270189 WP_111217666.1 NZ_CP117255:422924-423331 [Rhizobium tumorigenes]
VTTAATNFLDTNILIYAISDDRRAIQAQALLDLPFVVSGQTLNEFANVARKKLSMSWQDTSTAIEAIVSISTLVVPVDEK
VTLAALKLAPLYNLSFYDAAMIAAALQAGCKQYYSEDMQHGLVVEKHLTIVNPFH

Download         Length: 408 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8557.71 Da        Isoelectric Point: 5.0923

>AT270189 WP_111217664.1 NZ_CP117255:422697-422927 [Rhizobium tumorigenes]
MQVAKWGNSLAIRIPSSVVDALDLKEGDDISVSISNDCAVEIERDDRRLKALERIKSFGVKLPVDWKFDRNDANAR

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References