Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-MazE
Location 182559..183148 Replicon chromosome
Accession NZ_CP117255
Organism Rhizobium tumorigenes strain 1078

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag PR017_RS00925 Protein ID WP_111216718.1
Coordinates 182819..183148 (+) Length 110 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag PR017_RS00920 Protein ID WP_111216716.1
Coordinates 182559..182819 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PR017_RS00915 (PR017_00915) 180700..182496 + 1797 WP_111216715.1 acyl-CoA dehydrogenase C-terminal domain-containing protein -
PR017_RS00920 (PR017_00920) 182559..182819 + 261 WP_111216716.1 antitoxin Antitoxin
PR017_RS00925 (PR017_00925) 182819..183148 + 330 WP_111216718.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
PR017_RS00930 (PR017_00930) 183193..184401 + 1209 WP_111216720.1 acetyl-CoA C-acetyltransferase -
PR017_RS00935 (PR017_00935) 184404..184787 + 384 WP_111216722.1 cupin domain-containing protein -
PR017_RS00940 (PR017_00940) 184804..187014 + 2211 WP_111216724.1 3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein -
PR017_RS00945 (PR017_00945) 187392..187733 - 342 WP_111216726.1 oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-108)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 11956.69 Da        Isoelectric Point: 9.1988

>T270188 WP_111216718.1 NZ_CP117255:182819-183148 [Rhizobium tumorigenes]
MERGEIWFVDLEPTRGREQANERYAMILSPKVVNQHGTQIVAPITTGGQFARTSGFAVSLSGAGTRSTGVVLCHQIRAVD
IKARRGRFVEKAPDFIVDEVLARVAALFD

Download         Length: 330 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9639.94 Da        Isoelectric Point: 4.1954

>AT270188 WP_111216716.1 NZ_CP117255:182559-182819 [Rhizobium tumorigenes]
MVASTLRNVGGSLVMTVPKAITDELGLQANTKFDVTAQDGNIIAVPRRRPKYTVEQLVAEWEVWPERTAEEQEWLDMPSV
GNEIIE

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References