270081

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsaAT/-
Location 852825..853302 Replicon chromosome
Accession NZ_CP117203
Organism Staphylococcus aureus strain 2022QW-00133

Toxin (Protein)


Gene name TsaT Uniprot ID Q2G005
Locus tag PQQ74_RS04080 Protein ID WP_000052078.1
Coordinates 852825..853013 (-) Length 63 a.a.

Antitoxin (Protein)


Gene name TsaA Uniprot ID T1Y6P8
Locus tag PQQ74_RS04085 Protein ID WP_001059690.1
Coordinates 853042..853302 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQQ74_RS04050 (848866) 848866..849336 + 471 WP_000824472.1 hypothetical protein -
PQQ74_RS04055 (849677) 849677..850363 + 687 WP_001548082.1 thermonuclease family protein -
PQQ74_RS04060 (850720) 850720..850920 + 201 WP_001059082.1 cold-shock protein -
PQQ74_RS04065 (851416) 851416..851634 - 219 WP_000005886.1 hypothetical protein -
PQQ74_RS04070 (851696) 851696..851980 - 285 WP_001004395.1 hypothetical protein -
PQQ74_RS04075 (852068) 852068..852637 - 570 WP_001106654.1 lipoprotein N-acylation protein LnsA -
PQQ74_RS04080 (852825) 852825..853013 - 189 WP_000052078.1 hypothetical protein Toxin
PQQ74_RS04085 (853042) 853042..853302 - 261 WP_001059690.1 hypothetical protein Antitoxin
PQQ74_RS04090 (853643) 853643..853846 + 204 WP_000145163.1 sterile alpha motif-like domain-containing protein -
PQQ74_RS04095 (853843) 853843..854079 - 237 WP_000368687.1 hypothetical protein -
PQQ74_RS04100 (854304) 854304..854885 + 582 WP_001140686.1 histidine phosphatase family protein -
PQQ74_RS04105 (854958) 854958..855575 - 618 WP_000255561.1 LysE/ArgO family amino acid transporter -
PQQ74_RS04110 (855730) 855730..856224 - 495 WP_000569884.1 GNAT family N-acetyltransferase -
PQQ74_RS04115 (856623) 856623..857045 - 423 WP_000974448.1 organic hydroperoxide resistance protein -
PQQ74_RS04120 (857193) 857193..857909 + 717 WP_000150017.1 type I 3-dehydroquinate dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 63 a.a.        Molecular weight: 7172.84 Da        Isoelectric Point: 9.9971

>T270081 WP_000052078.1 NZ_CP117203:c853013-852825 [Staphylococcus aureus]
MSLHFAILFWLALIFLVAATFILVLMKKTSKESKKESYLSFTVILYIFGFAILIYTFIFGVL

Download         Length: 189 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9940.09 Da        Isoelectric Point: 4.0624

>AT270081 WP_001059690.1 NZ_CP117203:c853302-853042 [Staphylococcus aureus]
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYSFIG

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0D6HZ40

Antitoxin

Source ID Structure
AlphaFold DB A0A0E0VN56

References