Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Doc-RelB
Location 355964..356559 Replicon plasmid unnamed1
Accession NZ_CP117200
Organism Pantoea sp. SS70

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag PO881_RS21255 Protein ID WP_271460590.1
Coordinates 355964..356341 (-) Length 126 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag PO881_RS21260 Protein ID WP_110867236.1
Coordinates 356338..356559 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PO881_RS21235 (PO881_21235) 352564..353877 + 1314 WP_280173283.1 cytochrome c -
PO881_RS21240 (PO881_21240) 353988..354452 - 465 WP_210080080.1 heme-degrading domain-containing protein -
PO881_RS21245 (PO881_21245) 354535..354885 - 351 WP_192414734.1 cupin domain-containing protein -
PO881_RS21250 (PO881_21250) 355031..355954 + 924 WP_280173284.1 glutaminase B -
PO881_RS21255 (PO881_21255) 355964..356341 - 378 WP_271460590.1 type II toxin-antitoxin system death-on-curing family toxin Toxin
PO881_RS21260 (PO881_21260) 356338..356559 - 222 WP_110867236.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
PO881_RS21265 (PO881_21265) 356806..357222 + 417 WP_137387179.1 DUF2946 domain-containing protein -
PO881_RS21270 (PO881_21270) 357295..359031 + 1737 WP_280173285.1 DUF2534 family protein -
PO881_RS21275 (PO881_21275) 359112..360128 - 1017 WP_008108001.1 NAD(P)-dependent alcohol dehydrogenase -
PO881_RS21280 (PO881_21280) 360251..360520 - 270 WP_101761136.1 hypothetical protein -
PO881_RS21285 (PO881_21285) 360800..361360 + 561 WP_217547695.1 thioredoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - hcp/tssD 1..779368 779368


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Death on curing protein

(3-119)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-53)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 13948.02 Da        Isoelectric Point: 6.9889

>T270077 WP_271460590.1 NZ_CP117200:c356341-355964 [Pantoea sp. SS70]
MIHVSAEEVIALHDYLLKRYAGVAGMSDPGRAEAIVARVINREYYEGIQDIFELAATYWVAISRGHIFADANKRTSLNVT
MLFLKRNGIRVHDRPELVELTVMAATGEAGVPYLANQLRAFFGSH

Download         Length: 378 bp

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8005.92 Da        Isoelectric Point: 4.5203

>AT270077 WP_110867236.1 NZ_CP117200:c356559-356338 [Pantoea sp. SS70]
MNKFTYTSARENLSQVLDQAIAGEAVEITRRSGDSAVVISKASFEAYRKAVLDAEFAELMGEFDASNKALTDR

Download         Length: 222 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References