Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 343141..343691 Replicon plasmid unnamed1
Accession NZ_CP117200
Organism Pantoea sp. SS70

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag PO881_RS21190 Protein ID WP_101761119.1
Coordinates 343383..343691 (+) Length 103 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag PO881_RS21185 Protein ID WP_192413436.1
Coordinates 343141..343380 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PO881_RS21165 (PO881_21165) 338913..340079 + 1167 WP_280173278.1 lycopene beta-cyclase CrtY -
PO881_RS21170 (PO881_21170) 340076..341557 + 1482 WP_192413424.1 phytoene desaturase -
PO881_RS21175 (PO881_21175) 341554..342483 + 930 WP_280173279.1 phytoene/squalene synthase family protein -
PO881_RS21180 (PO881_21180) 342422..342955 - 534 WP_210080072.1 sterol desaturase family protein -
PO881_RS21185 (PO881_21185) 343141..343380 + 240 WP_192413436.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
PO881_RS21190 (PO881_21190) 343383..343691 + 309 WP_101761119.1 CcdB family protein Toxin
PO881_RS21195 (PO881_21195) 343823..345013 + 1191 WP_280173280.1 MFS transporter -
PO881_RS21200 (PO881_21200) 345006..345350 - 345 WP_280173281.1 helix-turn-helix transcriptional regulator -
PO881_RS21205 (PO881_21205) 345447..346388 - 942 WP_192413442.1 sugar phosphate isomerase/epimerase -
PO881_RS21210 (PO881_21210) 346397..347575 - 1179 WP_110867019.1 Gfo/Idh/MocA family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - hcp/tssD 1..779368 779368


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-101)

Antitoxin

Post-segregation antitoxin CcdA

(9-79)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 12049.95 Da        Isoelectric Point: 7.0106

>T270076 WP_101761119.1 NZ_CP117200:343383-343691 [Pantoea sp. SS70]
MQYFIYRNTNRNSEYPYLVDVQSEIIGELASRIVIPLYPLKQFKKKQVERLNPVIKVEGEEFLVMTHEMASVRVSLLGDQ
VMDARVYRQRIKDSVDFVFDGF

Download         Length: 309 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9019.16 Da        Isoelectric Point: 6.4696

>AT270076 WP_192413436.1 NZ_CP117200:343141-343380 [Pantoea sp. SS70]
MPSTAVRQKKTVSVTLEPALLEQAREAGLNLSAILSKALQHEIRTTQAERWKRENSEGLQELNRITEEHGLLSDEYRTF

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References