Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PP_4151-4152/excise(antitoxin) |
| Location | 335423..336459 | Replicon | plasmid unnamed1 |
| Accession | NZ_CP117200 | ||
| Organism | Pantoea sp. SS70 | ||
Toxin (Protein)
| Gene name | PP_4152 | Uniprot ID | - |
| Locus tag | PO881_RS21145 | Protein ID | WP_280173275.1 |
| Coordinates | 335423..335998 (-) | Length | 192 a.a. |
Antitoxin (Protein)
| Gene name | PP_4151 | Uniprot ID | - |
| Locus tag | PO881_RS21150 | Protein ID | WP_280173276.1 |
| Coordinates | 335998..336459 (-) | Length | 154 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PO881_RS21125 (PO881_21125) | 330638..331129 | - | 492 | WP_192413413.1 | GNAT family N-acetyltransferase | - |
| PO881_RS21130 (PO881_21130) | 331569..332996 | + | 1428 | WP_280173272.1 | trehalose-6-phosphate synthase | - |
| PO881_RS21135 (PO881_21135) | 333040..334221 | - | 1182 | WP_280173273.1 | FAD-binding oxidoreductase | - |
| PO881_RS21140 (PO881_21140) | 334340..335281 | - | 942 | WP_280173274.1 | 2-hydroxyacid dehydrogenase | - |
| PO881_RS21145 (PO881_21145) | 335423..335998 | - | 576 | WP_280173275.1 | PIN domain-containing protein | Toxin |
| PO881_RS21150 (PO881_21150) | 335998..336459 | - | 462 | WP_280173276.1 | helix-turn-helix domain-containing protein | Antitoxin |
| PO881_RS21155 (PO881_21155) | 336716..337621 | + | 906 | WP_192413419.1 | polyprenyl synthetase family protein | - |
| PO881_RS21160 (PO881_21160) | 337636..338913 | + | 1278 | WP_280173277.1 | glycosyltransferase | - |
| PO881_RS21165 (PO881_21165) | 338913..340079 | + | 1167 | WP_280173278.1 | lycopene beta-cyclase CrtY | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | hcp/tssD | 1..779368 | 779368 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 192 a.a. Molecular weight: 21379.89 Da Isoelectric Point: 5.2345
>T270075 WP_280173275.1 NZ_CP117200:c335998-335423 [Pantoea sp. SS70]
MNHSPYAVVLDACVLYPSILRDVLLRLGLTGLYQPKWTATIQEEWKRNLRTNRPDIAEDQLARTQTLMNKALPDAMVSGF
EPLISGITLPDSNDCHVVAAAIRCKAEVIVTMNLKDFPGNLLAEFEIEALHPDEFIMDLFDLNQALVLKAVNAQRASFRQ
PAMGVTVYLDSLLRQGLPMTVSALDKFHFLI
MNHSPYAVVLDACVLYPSILRDVLLRLGLTGLYQPKWTATIQEEWKRNLRTNRPDIAEDQLARTQTLMNKALPDAMVSGF
EPLISGITLPDSNDCHVVAAAIRCKAEVIVTMNLKDFPGNLLAEFEIEALHPDEFIMDLFDLNQALVLKAVNAQRASFRQ
PAMGVTVYLDSLLRQGLPMTVSALDKFHFLI
Download Length: 576 bp
Antitoxin
Download Length: 154 a.a. Molecular weight: 17094.52 Da Isoelectric Point: 6.6084
>AT270075 WP_280173276.1 NZ_CP117200:c336459-335998 [Pantoea sp. SS70]
MKHSILDSLSLPAPKEIEAALRGQRELATYLSTKQETQKISIQDAHNETHQIELPTSALTLLMAVLGELAVGNAVQVVPI
HAELTTQEAANILNVSRPHLVKLLEQGQLPYHKTGRHRRVLFADLMQFKDKRAQESNDAMQELANQGQDLNLY
MKHSILDSLSLPAPKEIEAALRGQRELATYLSTKQETQKISIQDAHNETHQIELPTSALTLLMAVLGELAVGNAVQVVPI
HAELTTQEAANILNVSRPHLVKLLEQGQLPYHKTGRHRRVLFADLMQFKDKRAQESNDAMQELANQGQDLNLY
Download Length: 462 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|