Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-HTH
Location 131489..132191 Replicon plasmid unnamed1
Accession NZ_CP117200
Organism Pantoea sp. SS70

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PO881_RS20195 Protein ID WP_280173185.1
Coordinates 131808..132191 (-) Length 128 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PO881_RS20190 Protein ID WP_101761582.1
Coordinates 131489..131815 (-) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PO881_RS20170 (PO881_20170) 127201..128088 + 888 WP_192413124.1 aromatic amino acid DMT transporter YddG -
PO881_RS20175 (PO881_20175) 128248..129450 - 1203 WP_192413126.1 FAD-dependent oxidoreductase -
PO881_RS20180 (PO881_20180) 129505..130440 - 936 WP_192413128.1 AraC family transcriptional regulator -
PO881_RS20185 (PO881_20185) 130553..131386 + 834 WP_192413130.1 oxidoreductase -
PO881_RS20190 (PO881_20190) 131489..131815 - 327 WP_101761582.1 helix-turn-helix domain-containing protein Antitoxin
PO881_RS20195 (PO881_20195) 131808..132191 - 384 WP_280173185.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PO881_RS20200 (PO881_20200) 132466..132717 + 252 WP_110866812.1 regulatory protein YcgZ -
PO881_RS20205 (PO881_20205) 132835..133125 + 291 WP_101761585.1 hypothetical protein -
PO881_RS20210 (PO881_20210) 133325..133675 - 351 WP_008102074.1 DUF3147 family protein -
PO881_RS20215 (PO881_20215) 133702..134565 - 864 WP_280173186.1 substrate-binding domain-containing protein -
PO881_RS20220 (PO881_20220) 134746..135141 + 396 WP_192413135.1 VOC family protein -
PO881_RS20225 (PO881_20225) 135254..135607 - 354 WP_192234707.1 DUF1428 domain-containing protein -
PO881_RS20230 (PO881_20230) 135786..136472 + 687 WP_110866982.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - hcp/tssD 1..779368 779368


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(1-123)

Antitoxin

Cro/C1-type helix-turn-helix domain

(50-96)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 13849.17 Da        Isoelectric Point: 10.2844

>T270073 WP_280173185.1 NZ_CP117200:c132191-131808 [Pantoea sp. SS70]
MAIYVLKPFDRNTKGDAINSAKLCKAALEVMAGIYEASFGRGVYKKRIPLVAGKSGGARAVVAFKTEKHLFFVNGYAKSA
FKSSGREISESDLALYKEVAKQLFEMTSEKAKVAINTGKMREVKCDG

Download         Length: 384 bp

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 12399.44 Da        Isoelectric Point: 8.5487

>AT270073 WP_101761582.1 NZ_CP117200:c131815-131489 [Pantoea sp. SS70]
MVNHLKDLQEIAKDFNEIGVVTDELKEKIDSRVRLRELRASLPVLHMMSGDEINQLRQRYNLSQAMLAAYVGMSVGTVVK
WEREEKKPNGAALRLLNLIERKGLEVLQ

Download         Length: 327 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References