Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 3598030..3598699 Replicon chromosome
Accession NZ_CP117199
Organism Pantoea sp. SS70

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag PO881_RS16485 Protein ID WP_280172099.1
Coordinates 3598030..3598359 (-) Length 110 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag PO881_RS16490 Protein ID WP_280172100.1
Coordinates 3598382..3598699 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PO881_RS16460 (PO881_16460) 3594699..3595214 - 516 WP_101762980.1 G/U mismatch-specific DNA glycosylase -
PO881_RS16465 (PO881_16465) 3595211..3595798 - 588 WP_110867321.1 TetR/AcrR family transcriptional regulator -
PO881_RS16470 (PO881_16470) 3595933..3596715 + 783 WP_280172097.1 SDR family oxidoreductase -
PO881_RS16480 (PO881_16480) 3597081..3597914 - 834 WP_280172098.1 DUF4942 domain-containing protein -
PO881_RS16485 (PO881_16485) 3598030..3598359 - 330 WP_280172099.1 TA system toxin CbtA family protein Toxin
PO881_RS16490 (PO881_16490) 3598382..3598699 - 318 WP_280172100.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
PO881_RS16495 (PO881_16495) 3598712..3599188 - 477 WP_280172101.1 DNA repair protein RadC -
PO881_RS16500 (PO881_16500) 3599203..3599616 - 414 WP_280172917.1 antirestriction protein -
PO881_RS16505 (PO881_16505) 3599741..3600148 - 408 WP_280172918.1 IrmA family protein -
PO881_RS16510 (PO881_16510) 3600178..3600627 - 450 WP_280172102.1 hypothetical protein -
PO881_RS16515 (PO881_16515) 3600643..3601272 - 630 WP_280172103.1 hypothetical protein -
PO881_RS16520 (PO881_16520) 3601269..3601985 - 717 WP_280172104.1 WYL domain-containing protein -
PO881_RS16525 (PO881_16525) 3602192..3603028 - 837 WP_280172105.1 DUF932 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3598030..3616929 18899


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-107)

Antitoxin

Antitoxin CbeA

(5-103)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 11957.59 Da        Isoelectric Point: 4.4315

>T270071 WP_280172099.1 NZ_CP117199:c3598359-3598030 [Pantoea sp. SS70]
MPTFSSHPERAASCCLSPTAHWRILLVYLLEKLFGLELNDTPFCSESVIQQHIEAGVTLVDAINFLVEKYDLVRVDTSSD
ACTESEIFLTAADILKASHATGLTQSNLS

Download         Length: 330 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 12030.58 Da        Isoelectric Point: 6.6335

>AT270071 WP_280172100.1 NZ_CP117199:c3598699-3598382 [Pantoea sp. SS70]
MNENEWGLKRSITPRFGARLVQEGNRLHYLADRAGIVGKFSEEQIDRINQSFPQMIGMLEHLLTTGELNPRQQHCITIYH
NNLTCEADTLGSHGYVYISVYPTPQ

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References