Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2712113..2712744 Replicon chromosome
Accession NZ_CP117199
Organism Pantoea sp. SS70

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PO881_RS12550 Protein ID WP_061717750.1
Coordinates 2712346..2712744 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PO881_RS12545 Protein ID WP_101763423.1
Coordinates 2712113..2712346 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PO881_RS12540 (PO881_12540) 2708970..2712041 + 3072 WP_280171870.1 multidrug efflux RND transporter permease subunit MdtC -
PO881_RS12545 (PO881_12545) 2712113..2712346 + 234 WP_101763423.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
PO881_RS12550 (PO881_12550) 2712346..2712744 + 399 WP_061717750.1 type II toxin-antitoxin system VapC family toxin Toxin
PO881_RS12555 (PO881_12555) 2712761..2714167 + 1407 WP_280171871.1 multidrug transporter subunit MdtD -
PO881_RS12560 (PO881_12560) 2714164..2715549 + 1386 WP_101763347.1 two-component system sensor histidine kinase BaeS -
PO881_RS12565 (PO881_12565) 2715559..2716266 + 708 WP_101763346.1 two-component system response regulator BaeR -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 15025.28 Da        Isoelectric Point: 8.0933

>T270070 WP_061717750.1 NZ_CP117199:2712346-2712744 [Pantoea sp. SS70]
MHRYMLDTNIVIYVIKRRPIEVLERFNANVGRMVISTITLAELFHGSEKSAFPERNLRTVEDFVSRLDVLNYDAKAAFHY
GAIRAELEKNGTPIGLNDLHIAAHARSAALTLVSNNLREFSRVNGLICENWI

Download         Length: 399 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8780.67 Da        Isoelectric Point: 4.2683

>AT270070 WP_101763423.1 NZ_CP117199:2712113-2712346 [Pantoea sp. SS70]
MSQGTVFTSNRTQNVRIPADVRFPDDVKNVTVRAIGKERILTPIENAWDSFFLDGPTVSDDFMDERASQEQSEREAF

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References