Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-MazE
Location 2617275..2617865 Replicon chromosome
Accession NZ_CP117199
Organism Pantoea sp. SS70

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag PO881_RS12155 Protein ID WP_277973770.1
Coordinates 2617275..2617607 (-) Length 111 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag PO881_RS12160 Protein ID WP_075808466.1
Coordinates 2617608..2617865 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PO881_RS12135 (PO881_12135) 2612436..2613467 - 1032 WP_101763421.1 ABC transporter permease -
PO881_RS12140 (PO881_12140) 2613482..2614966 - 1485 WP_101763420.1 sugar ABC transporter ATP-binding protein -
PO881_RS12145 (PO881_12145) 2615000..2615923 - 924 WP_101763419.1 sugar ABC transporter substrate-binding protein -
PO881_RS12155 (PO881_12155) 2617275..2617607 - 333 WP_277973770.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
PO881_RS12160 (PO881_12160) 2617608..2617865 - 258 WP_075808466.1 antitoxin Antitoxin
PO881_RS12165 (PO881_12165) 2618283..2619587 - 1305 WP_280171841.1 NtaA/DmoA family FMN-dependent monooxygenase -
PO881_RS12170 (PO881_12170) 2619599..2620798 - 1200 WP_280171842.1 M20 family metallopeptidase -
PO881_RS12175 (PO881_12175) 2620896..2621552 - 657 WP_192233454.1 methionine ABC transporter permease -
PO881_RS12180 (PO881_12180) 2621533..2622663 - 1131 WP_280171843.1 ATP-binding cassette domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-109)

Antitoxin

Antitoxin PemI-like

(4-84)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 11782.57 Da        Isoelectric Point: 9.3417

>T270068 WP_277973770.1 NZ_CP117199:c2617607-2617275 [Pantoea sp. SS70]
MDRGEIWLVSLDPIAGHEQSGKRPVLIVSKASFNTLTRLPVVVPVTSGGNFAREAGFTVSLDGAGTKTTGVIRCDQPRTI
DMGARNGKRLERIPDAVVNEVLARLEAILS

Download         Length: 333 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9414.97 Da        Isoelectric Point: 4.4620

>AT270068 WP_075808466.1 NZ_CP117199:c2617865-2617608 [Pantoea sp. SS70]
MYTTRLKKVGGSIMLAVPPAVLKTLELSMGSEVGMTIDNGCLIIEPQKRPRYSLEELLAQCDPHAEMSEEDREWIDAPAV
GKEIL

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References