Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 5903..6425 Replicon plasmid unnamed4
Accession NZ_CP117172
Organism Serratia proteamaculans strain CD3406

Toxin (Protein)


Gene name relE Uniprot ID A0A1Q5V3N4
Locus tag JET59_RS27745 Protein ID WP_074031970.1
Coordinates 6144..6425 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JET59_RS27740 Protein ID WP_219015177.1
Coordinates 5903..6154 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JET59_RS27715 (JET59_027715) 1186..2013 - 828 WP_219015173.1 HEPN domain-containing protein -
JET59_RS27720 (JET59_027720) 2024..2386 - 363 WP_219015174.1 DUF2726 domain-containing protein -
JET59_RS27725 (JET59_027725) 2598..3059 - 462 WP_219015175.1 hypothetical protein -
JET59_RS27730 (JET59_027730) 3069..4007 - 939 WP_219015190.1 replication initiation protein -
JET59_RS27735 (JET59_027735) 5149..5841 + 693 WP_219015176.1 hypothetical protein -
JET59_RS27740 (JET59_027740) 5903..6154 + 252 WP_219015177.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
JET59_RS27745 (JET59_027745) 6144..6425 + 282 WP_074031970.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JET59_RS27750 (JET59_027750) 6467..7027 + 561 WP_219015178.1 hypothetical protein -
JET59_RS27755 (JET59_027755) 7020..7289 + 270 WP_219015179.1 hypothetical protein -
JET59_RS27760 (JET59_027760) 7286..7720 + 435 WP_260329082.1 hypothetical protein -
JET59_RS27765 (JET59_027765) 8204..8719 + 516 WP_219015180.1 DnaJ domain-containing protein -
JET59_RS27770 (JET59_027770) 8831..9016 + 186 WP_219015181.1 hypothetical protein -
JET59_RS27775 (JET59_027775) 9143..9352 + 210 WP_126179359.1 hypothetical protein -
JET59_RS27780 (JET59_027780) 9548..9751 + 204 WP_219015182.1 hypothetical protein -
JET59_RS27785 (JET59_027785) 10202..10759 + 558 WP_219015183.1 DNA distortion polypeptide 1 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..46588 46588


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10949.85 Da        Isoelectric Point: 10.6485

>T270012 WP_074031970.1 NZ_CP117172:6144-6425 [Serratia proteamaculans]
MTYKLKFEKRALKEWEKLGHPIREQLKKKLAERLENPHVPASRLSGRQNRYKIKLRSSGYRLVYEVIDNEIVLLVIAVGK
RAGDEVYLTADKR

Download         Length: 282 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9190.31 Da        Isoelectric Point: 3.8705

>AT270012 WP_219015177.1 NZ_CP117172:5903-6154 [Serratia proteamaculans]
MAYQILTTTAASITDLKKNPMGTVADGDGEAVAILNRNEPAFYCVPPELYAYYRELAEDAELNQIADERMKNAEFVSVTL
DDL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1Q5V3N4

Antitoxin

Source ID Structure

References