Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RelE(toxin)
Location 5247698..5248263 Replicon chromosome
Accession NZ_CP117168
Organism Serratia proteamaculans strain CD3406

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag JET59_RS24680 Protein ID WP_219017132.1
Coordinates 5247985..5248263 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag JET59_RS24675 Protein ID WP_219017131.1
Coordinates 5247698..5247967 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JET59_RS24660 (JET59_024660) 5243918..5245135 - 1218 WP_099063534.1 aspartate aminotransferase family protein -
JET59_RS24665 (JET59_024665) 5245267..5245842 - 576 WP_219017130.1 aminodeoxychorismate synthase component II -
JET59_RS24670 (JET59_024670) 5245941..5247467 - 1527 WP_099063532.1 DUF853 family protein -
JET59_RS24675 (JET59_024675) 5247698..5247967 + 270 WP_219017131.1 hypothetical protein Antitoxin
JET59_RS24680 (JET59_024680) 5247985..5248263 + 279 WP_219017132.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JET59_RS24685 (JET59_024685) 5248264..5248989 - 726 WP_099063529.1 two-component system response regulator BtsR -
JET59_RS24690 (JET59_024690) 5248989..5250674 - 1686 WP_099063528.1 sensor histidine kinase -
JET59_RS24695 (JET59_024695) 5250836..5251405 - 570 WP_099063527.1 peptidylprolyl isomerase A -
JET59_RS24700 (JET59_024700) 5251762..5252100 + 339 WP_219017212.1 PTS lactose/cellobiose transporter subunit IIA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10127.78 Da        Isoelectric Point: 9.8649

>T270010 WP_219017132.1 NZ_CP117168:5247985-5248263 [Serratia proteamaculans]
VKLKWTEPAIADRMAIYDYLASKNPVAAAEIDALISAATARLSQNPLSGKPGRAPGTRELVIHHSYLLIYELTNGPLIIL
AVVHARRQWPKD

Download         Length: 279 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10475.81 Da        Isoelectric Point: 4.9566

>AT270010 WP_219017131.1 NZ_CP117168:5247698-5247967 [Serratia proteamaculans]
MSESTVVIRVDDELKMAFASAAKAADRTASQLLRDFMRDFVCRQSQQKEYEQWLQEKVEISRKALHEGKIVDDEDVEAYF
AERREKSMR

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References