Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4584687..4585356 Replicon chromosome
Accession NZ_CP117168
Organism Serratia proteamaculans strain CD3406

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag JET59_RS21480 Protein ID WP_099063843.1
Coordinates 4584687..4585109 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A2X2G343
Locus tag JET59_RS21485 Protein ID WP_037418284.1
Coordinates 4585090..4585356 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JET59_RS21460 (JET59_021460) 4580571..4581089 + 519 WP_085118696.1 flavodoxin FldB -
JET59_RS21465 (JET59_021465) 4581130..4582494 - 1365 WP_219016885.1 cell envelope integrity protein CreD -
JET59_RS21470 (JET59_021470) 4582577..4583995 - 1419 WP_219016886.1 two-component system sensor histidine kinase CreC -
JET59_RS21475 (JET59_021475) 4583992..4584687 - 696 WP_085118700.1 two-component system response regulator CreB -
JET59_RS21480 (JET59_021480) 4584687..4585109 - 423 WP_099063843.1 protein YgfX Toxin
JET59_RS21485 (JET59_021485) 4585090..4585356 - 267 WP_037418284.1 FAD assembly factor SdhE Antitoxin
JET59_RS21490 (JET59_021490) 4585680..4586672 + 993 WP_099063844.1 tRNA-modifying protein YgfZ -
JET59_RS21495 (JET59_021495) 4586758..4587432 - 675 WP_085118705.1 hemolysin III family protein -
JET59_RS21500 (JET59_021500) 4587616..4588224 + 609 WP_099063845.1 HD domain-containing protein -
JET59_RS21505 (JET59_021505) 4588275..4589600 - 1326 WP_219016887.1 MFS transporter -
JET59_RS21510 (JET59_021510) 4589597..4590250 - 654 WP_219016888.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16439.32 Da        Isoelectric Point: 10.5155

>T270009 WP_099063843.1 NZ_CP117168:c4585109-4584687 [Serratia proteamaculans]
VAQWRCDVRISWRTQLLSLLTHGALILLILISPWPEGYGPIWLVLLTLVVFECIRSQKRIASRQGELRLLENQRLGWHGQ
EWQLVKQPWMPRYGILLTLQPVGGKKRRRLWLASDAMAKADWRHLRQQLLYPPASDDEEP

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10472.93 Da        Isoelectric Point: 4.7921

>AT270009 WP_037418284.1 NZ_CP117168:c4585356-4585090 [Serratia proteamaculans]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDQLNDTDKALFIRLLESDDPDLFNWLMNHGAPQDSELQRMVTLIQTRN
KDRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2X2G343

References