Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 4193720..4194372 Replicon chromosome
Accession NZ_CP117168
Organism Serratia proteamaculans strain CD3406

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JET59_RS19670 Protein ID WP_099062615.1
Coordinates 4193720..4194106 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JET59_RS19675 Protein ID WP_112348659.1
Coordinates 4194109..4194372 (-) Length 88 a.a.

Genomic Context

JET59_RS19655JET59_RS19660JET59_RS19665JET59_RS19680JET59_RS19685JET59_RS19690JET59_RS19670JET59_RS19675
Location: 4190188..4191618 (1431 bp)
Type: Others
Protein ID: WP_099062612.1
Location: 4191615..4192997 (1383 bp)
Type: Others
Protein ID: WP_219016767.1
Location: 4192997..4193713 (717 bp)
Type: Others
Protein ID: WP_219016796.1
Location: 4194727..4195065 (339 bp)
Type: Others
Protein ID: WP_099062617.1
Location: 4195244..4196596 (1353 bp)
Type: Others
Protein ID: WP_219016768.1
Location: 4197086..4198003 (918 bp)
Type: Others
Protein ID: WP_099062619.1
Location: 4193720..4194106 (387 bp)
Type: Toxin
Protein ID: WP_099062615.1
Location: 4194109..4194372 (264 bp)
Type: Antitoxin
Protein ID: WP_112348659.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
JET59_RS19655 (JET59_019655)4190188..4191618+1431WP_099062612.1MFS transporter-
JET59_RS19660 (JET59_019660)4191615..4192997+1383WP_219016767.1two-component system sensor histidine kinase BaeS-
JET59_RS19665 (JET59_019665)4192997..4193713+717WP_219016796.1two-component system response regulator BaeR-
JET59_RS19670 (JET59_019670)4193720..4194106-387WP_099062615.1type II toxin-antitoxin system VapC family toxinToxin
JET59_RS19675 (JET59_019675)4194109..4194372-264WP_112348659.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
JET59_RS19680 (JET59_019680)4194727..4195065+339WP_099062617.1YegP family protein-
JET59_RS19685 (JET59_019685)4195244..4196596+1353WP_219016768.1tRNA 5-hydroxyuridine modification protein YegQ-
JET59_RS19690 (JET59_019690)4197086..4198003+918WP_099062619.1lipid kinase YegS-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-119)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14192.53 Da        Isoelectric Point: 9.5368

>T270008 WP_099062615.1 NZ_CP117168:c4194106-4193720 [Serratia proteamaculans]
MYMFDTNTVSQLFRRHPRLLRVMEKIPPSAVCISSITEAELLYGVAKRQSLALKATVAAFLDSVTVYAWDREAAHCYGTM
RADMAKKGRVMGALDQLIAAHAQSRGATIVTNDKAFAMVPGLRVEDWT

Download         Length: 387 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 10206.55 Da        Isoelectric Point: 4.6702

>AT270008 WP_112348659.1 NZ_CP117168:c4194372-4194109 [Serratia proteamaculans]
MERVAKLFKNGRNQAVRLPVEFEFDTDRVYIRRDREGNVILSKYPAKPDSWAPLLQMIEQTQVPQDFLVAEDRQQGIAIR
DPFGEEE

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References