Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 4193720..4194372 Replicon chromosome
Accession NZ_CP117168
Organism Serratia proteamaculans strain CD3406

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JET59_RS19670 Protein ID WP_099062615.1
Coordinates 4193720..4194106 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JET59_RS19675 Protein ID WP_112348659.1
Coordinates 4194109..4194372 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JET59_RS19655 (JET59_019655) 4190188..4191618 + 1431 WP_099062612.1 MFS transporter -
JET59_RS19660 (JET59_019660) 4191615..4192997 + 1383 WP_219016767.1 two-component system sensor histidine kinase BaeS -
JET59_RS19665 (JET59_019665) 4192997..4193713 + 717 WP_219016796.1 two-component system response regulator BaeR -
JET59_RS19670 (JET59_019670) 4193720..4194106 - 387 WP_099062615.1 type II toxin-antitoxin system VapC family toxin Toxin
JET59_RS19675 (JET59_019675) 4194109..4194372 - 264 WP_112348659.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
JET59_RS19680 (JET59_019680) 4194727..4195065 + 339 WP_099062617.1 YegP family protein -
JET59_RS19685 (JET59_019685) 4195244..4196596 + 1353 WP_219016768.1 tRNA 5-hydroxyuridine modification protein YegQ -
JET59_RS19690 (JET59_019690) 4197086..4198003 + 918 WP_099062619.1 lipid kinase YegS -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-119)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14192.53 Da        Isoelectric Point: 9.5368

>T270008 WP_099062615.1 NZ_CP117168:c4194106-4193720 [Serratia proteamaculans]
MYMFDTNTVSQLFRRHPRLLRVMEKIPPSAVCISSITEAELLYGVAKRQSLALKATVAAFLDSVTVYAWDREAAHCYGTM
RADMAKKGRVMGALDQLIAAHAQSRGATIVTNDKAFAMVPGLRVEDWT

Download         Length: 387 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 10206.55 Da        Isoelectric Point: 4.6702

>AT270008 WP_112348659.1 NZ_CP117168:c4194372-4194109 [Serratia proteamaculans]
MERVAKLFKNGRNQAVRLPVEFEFDTDRVYIRRDREGNVILSKYPAKPDSWAPLLQMIEQTQVPQDFLVAEDRQQGIAIR
DPFGEEE

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References