Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 4159904..4160371 Replicon chromosome
Accession NZ_CP117168
Organism Serratia proteamaculans strain CD3406

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag JET59_RS19555 Protein ID WP_219016758.1
Coordinates 4159904..4160173 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JET59_RS19560 Protein ID WP_099062595.1
Coordinates 4160177..4160371 (-) Length 65 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JET59_RS19525 (JET59_019525) 4155098..4155613 + 516 WP_129936911.1 E3 ubiquitin--protein ligase -
JET59_RS19530 (JET59_019530) 4155644..4155892 + 249 WP_006316897.1 GlsB/YeaQ/YmgE family stress response membrane protein -
JET59_RS19535 (JET59_019535) 4155945..4157234 - 1290 WP_112348682.1 uracil permease -
JET59_RS19540 (JET59_019540) 4157296..4157922 - 627 WP_017893631.1 uracil phosphoribosyltransferase -
JET59_RS19545 (JET59_019545) 4158178..4159215 + 1038 WP_085118131.1 phosphoribosylformylglycinamidine cyclo-ligase -
JET59_RS19550 (JET59_019550) 4159215..4159853 + 639 WP_219016757.1 phosphoribosylglycinamide formyltransferase -
JET59_RS19555 (JET59_019555) 4159904..4160173 - 270 WP_219016758.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JET59_RS19560 (JET59_019560) 4160177..4160371 - 195 WP_099062595.1 hypothetical protein Antitoxin
JET59_RS19565 (JET59_019565) 4160518..4161072 + 555 WP_099062596.1 spermidine N1-acetyltransferase -
JET59_RS19570 (JET59_019570) 4161151..4161963 - 813 WP_085118133.1 phosphate ABC transporter ATP-binding protein PstB -
JET59_RS19575 (JET59_019575) 4161992..4163644 - 1653 WP_207979918.1 phosphate ABC transporter permease PstA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10548.18 Da        Isoelectric Point: 6.4826

>T270007 WP_219016758.1 NZ_CP117168:c4160173-4159904 [Serratia proteamaculans]
MRIEWSSEAQEELWSIIDYIDDRNPQAARKLHREIEAVVLTLPLNPLMYRLGRVDNTREIVVHPNYLVVYRVIGHIEVLS
VIHAKREYP

Download         Length: 270 bp

Antitoxin


Download         Length: 65 a.a.        Molecular weight: 7317.49 Da        Isoelectric Point: 10.3798

>AT270007 WP_099062595.1 NZ_CP117168:c4160371-4160177 [Serratia proteamaculans]
MAIKPPLSTLPVLGSAEQTESYDRWYRAKVESAINSEQPRISHEQVMTEMQTRLAAKKKLRKMG

Download         Length: 195 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References